Monoclonal ab/biologics Flashcards
1
Q
infixumab, adalimumab, ETANERCEPT
A
TNF alpha monoclonal antibodies, 1gG1 class. Can induce apoptosis. Some not igG some igM
2
Q
Abatacept
A
decativates t cell, targets CD80/86
3
Q
canakinumab
A
IL-1 target
4
Q
Tocilizumab
A
IL-6 target
5
Q
Rituximab
A
CD20 on bcell, high risk of infection
6
Q
tofacitinib
A
targets JAK, Decreases overactive tyrosine kinase. High risk of infection