glucocorticoids

Question 1

Etomidatte/metyrapone

Answer 1

blocks cortisol production by inhibiting CYP11B1

can be given to see if a patient has adrenal insufficiency at either the adrenal gland or the hypothalamic-pituitary axis

Question 2

hydrocortisone

Answer 2

anti finlammatory, good for adrenal insufficiency

inducer of cyp450

Question 3

dexamethasone

Answer 3

more intense
can dx cushings syndrome, aid in fetal lung development by increasing surfectant production
Can be utilized to help provide relief of clinical symptoms of CINV; help to increase efficacy by being a serotonin antagonist & promoting the release of endorphins to help with relief of symptoms

Question 4

prednisone

Answer 4

immunosuppressive and anti infkammatory

Question 5

triamcinolone

Answer 5

first line for cortisone responses dermatoses

Question 6

mifepristone

Answer 6

Glucocorticoid antagonist

Used to treat hypercortisolism and at lower does as an anti-progestin for termination of early pregnancy

Question 7

Tetracosactide or cosyntropin

Answer 7

test for addisons

Question 8

ketoconazole

Answer 8

blocks cyp17 and cyp11 to block steroid synthesis, blcoks downstream hormones, high doses

Question 9

GLUCOCORTICOIDS CAN BE.

Answer 9

absorbed orally, iv, and Im(later release)

Question 10

glucocorticoids can induce

Answer 10

P450 cytochrome enzymes.

Question 11

Fludrocortisone

Answer 11

strong mineralo-activity