Monoamines Flashcards
1
Q
All monoamine transporters are GPCR except which
A
5HT 3
2
Q
Pathway to Adrenaline from precursor
A
Phenylalanine Tyrosine L dopa Dopamine Noradrenaline Adrenaline
3
Q
What does MOA-A break down (3)
A
Serotonin
NA
Adrenaline
4
Q
What does MAO-B breakdown
A
Phenylethylamine
Benzylamine
5
Q
MAO-A/B breakdown
A
Dopamine
Tryamine
Tryptamine
6
Q
What does COMT breakdown
A
Dopamine
7
Q
What receptros are in D1 like family
A
D1
D5
8
Q
What recepotors are in D2 family
A
D2
d3
d4
9
Q
What do D1 family couple
A
Gs
Increase cAMP
10
Q
What do D2 like couple
A
Gi/o
Decrease cAMP
Activation of K channels
11
Q
Dopamine functions
A
Blood vessel vasodilation GI tract motility Insulin production Sodium excretion in kidney CNS motor control/reward
12
Q
What is alpha 1 adrenoreceptor coupled to
A
Gq
13
Q
What is a2 adreno coupled to
A
gi/o
14
Q
What are Beta adrenorectpor coupled to
A
Gs
15
Q
Serotonin fuctions
A
GI motilily Pain modulation Sleep/wake Nausea and appetite Memory and learning Mood and fear
