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Neuropharm > Epilepsy drug mechansims > Flashcards

Epilepsy drug mechansims Flashcards

1
Q

Phenytoin mechanism of action

A

Na/Ca channel block

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2
Q

Carbamazepine mechanism of action

A

Na/Ca channel block

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3
Q

Ethosuximide

A

Ca channel block

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4
Q

Valporate

A

Increase Gaba levels / Ca channel block

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5
Q

Vigabatrin

A

Inhibits GABA transaminase - Increase GABA levels

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6
Q

Tiagabine

A

Blocks GABA transporters GAT1 AND GAT3 - increase GABA

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7
Q

Benzos

A

Enhance GABA receptors

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8
Q

Barbituates

A

Enhance GABA receptors

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9
Q

Lamotragine

A

Na channel block, reduces glutamate release

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10
Q

Felbutmate

A

Na block/ GABA potentiation

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11
Q

Topiramate

A

Na channel block / reduces glutamate release / GABA potentiation

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12
Q

Gabapentin/ Pregabalin

A

Ca channel blockers

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13
Q

Zonisamide

A

Na and T type Ca channel blocker

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Neuropharm (15 decks)

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