Mollicutes: Mycoplasma and Ureoplasma Flashcards
What is special about Mycoplasmas cell wall?
NOTHING! It doesn’t have a cell wall!
[not capable for synthesizing cell wall precursors, trilaminar membrane provides sufficient osmotic stability for survival]
Which species of Mycoplasma causes feline infectious anemia?
M. hemofelis
The family of Mycoplasma and Ureaplasma require an exogenous source of what?
What does Mycoplasma require?
What about Ureaplasma?
Require exogenous source of cholesterol (add it to media to grow)
Mycoplasma - most require glucose or arginine
Ureaplasma - require urea
What tissues will Mycoplasma and Ureaplasma inhabit?
Mucous membranes
[especially in respiratory and reproductive tracts]
[obligate parasites]
When grown in vitro, what appearance do Mycoplasama colonies have?
“fried egg” appearance
What kind of infection does Mycoplasma cause?
Persistent infection within host - typically chronic with long incubation periods and mild clinical signs
Which species of Mycoplasma causes enzootic swine pneumonia?
M. hyopneumoniae
Which Mycoplasma is associated with shipping fever?
M. bovis
Which species of Mycoplasma causes infectious sinusitis in turkers and airsacculitis in chickens?
M. gallisepticum
Which species of Mycoplasma causes contagious bovine pleuropneumonia?
M. mycoides subsp. mycoides
[not in the USA]
Which species of Mycoplasma causes contagious caprine pleuropneumonia?
M. capricolum subsp. capripneumoniae
[Reportable in US]
Which species of Mycoplasma causes contagious agalactia of sheep and goats?
M. agalactiae and M. putrefaciens
Which species of Mycoplasma causes urogenital tract infections and abortions in cows?
M. bovisgenitalium (lol)
Which species of Mycoplasma causes mastitis and respiratory infections?
M. bovis
Which species of Mycoplasma causes pneumonia and inflammation of joints in calves?
M. bovis or M. dispar
Which species of Mycoplasma causes septicemia, arthritis and mastitis in caprines?
M. capricolum subsp. capricolum
Which species of Mycoplasma causes a systemic infection in young pigs with polyserositis?
M. hyorhinis
Which species of Mycoplasma causes arthritis in growing pigs 3-6 months of age?
M. hyosynoviae
What kind of antimicrobials can you not use in a Mycoplasma infection?
Which ones are recommended for treatment?
Cell wall active drugs - cause it doesn’t have one duh
Tetracyclines, lincosamides, fluoroquinolones
What is special about hemocytotrophic Mycoplasma?
They are pierythrocyctic extracellular parasites
[H. haemofelis, H. haemosuis]
What is the principle target cell for M. haemosuis and M. haemofelis?
Erythrocytes
What does M. haemofelis cause? What are the clinical signs?
Feline infectious anemia
Fever, anemia, depression, weakness, icterus
What stain can you use to ID M. haemofelis?
Wright/Giemsa stain
What disease does M. haemosuis cause? What are the clinical signs?
Eperythrozoonosis
What tests would you use to diagnose haemocytotrophic mycoplasma?
CBC and Coombs test
Which antibiotics would you use to treat haemocytotrophic mycoplasma?
Doxycycline and fluoroquinolone
