Chlamydia

Question 1

True/False. Chlaydiales are obligate intracellular bacteria.

Answer 1

True.

Question 2

Where does Chlamydiales replicate? What kind of inclusions would you see on light microscopy?

Answer 2

Replicate in phagosomes

Cytoplasmic inclusions

Question 3

What is the intracellular replicating form of Chalmydiales in the dimorphic life cycle called?

Answer 3

Reticulate body

Question 4

What is the extracellular non-replicating form of Chalmydiales in the dimorphic life cycle called?

Answer 4

Elementary body

Question 5

Which is the infectious stage: reticulate body? elementary body? or both?

Answer 5

elementary body

“spore-like” body whos purpsoe is to allow survival in the environmentn — resistant

Question 6

Reticulate bodies divide by what?? What do they mature into??

Answer 6

Divide by binary fission

Mature into smaller elementary bodies - this means they are metabolically

Question 7

How is infection initiated with Chlamydiales?

Answer 7

Infection is initiated by attachment of the chlamydial EB to the host cell, via microvilli

Question 8

When entering the host cell how does Chlamydiales protects itself?

Answer 8

Organism protects itself by inhibiting fusion of endosome with lysosomes

[some spp endosomes w/organisms fuse together into single inclusion] -idkk its on the ppt

Question 9

True/False. Inapparent infections are common with Chlamydia.

Answer 9

True

Question 10

Which species of Chlamydia is zoonotic?

Answer 10

Chlamydia psittaci

Question 11

Which species of Chlamydia infects humans?

Answer 11

C. trachomatis

STD!!!! (the clap?)

Question 12

Which species of Chlamydia causes conjunctivitis in cats?

Answer 12

C. felis

[known agent of feline pneumonitis]

[endemic in housecats worldwide]

Question 13

Which species of Chlamydia causes abortions in ruminants? What specifically in ewes?

Answer 13

C. abortus (duh)

Enzootic abortion of ewes

Question 14

Which species of Chlamydia causes polyarthritis and polyserositis in ruminants, also called “stiff lamb disease”?

Answer 14

C. pecorm

[also causes sporadic abortion, enteritis, pneumonia, conjunctivitis and mastitis]

Question 15

Is C. psittaci reportable in birds?

Answer 15

YES!! REPORT! BSL-3

Chlamydiosis, ornithosis or psittacosis - all the same name for the disease caused in birds by Chlamydia

[street name: parrot fever]

Question 16

What kind of infection is Chlamydiosis in birds?

Answer 16

Upper respiratory tract

[will also see enlarged liver and spleen]

Question 17

Which special stains are commonly used for Chlamydiales?

Answer 17

Gimenez

Machiavello

Giemsa stain

Question 18

Which species of Chlamydia causes sporadic bovine encephalomyelitis?

What kind of disease is this? Does it affect old or young cattle?

Answer 18

C. pecorum

Febrile diseases mainly in young cattle

Question 19

Which antibiotic is Chlamydia susceptible to?

Answer 19

Tetracyclines

[its not forever you dirty whores]