Molecular Biology History Flashcards

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1
Q

Johann Friedrich Miescher 1869

A
  • identifies a weakly acidic substance in the nuclei of cells
  • this substance will later be called deoxyribonucleic acid or DNA
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2
Q

Brogg and William 1912

A

X-ray diffraction patterns

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3
Q

1924

A

microscope studies using stains for DNA and protein show that both substances are present in chromosomes

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4
Q

Griffith 1928

A

studied Streptococcus pneumonia (a bacteria that causes pneumonia)
1) smooth (surrounded by mucous coat/capsule)
2) rough

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5
Q

Avery, McCarty, Macleod 1944

A

the transforming agent was DNA

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6
Q

Hershey, Chase 1952

A
  • used radioactively labelled viruses to confirm that DNA is the hereditary material
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7
Q

Franklin 1950s

A
  • took x-ray diffraction patterns of DNA
  • suggested the shape was a double helix
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8
Q

Watson and Crick 1953

A
  • published the discovery of the structure of DNA
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