module 4 - cell membrane transport Flashcards

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1
Q

what do cell membranes contain

A

specialized membrane protein and transport proteins

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2
Q

what does membrane transport proteins facilitate?

A

passage of small water soluble molecules

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3
Q

what are lipid bilayers impermeable to ?

A

ions and most uncharged polar molecules

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4
Q

what determines diffusion rate

A

molecule’s size and solubility

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5
Q

diffusion

A

dye molecules move to become evenly distributed (goes from initial –> diffusion —> final)

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6
Q

what are the inorganic ions for cells?

A

Na, K, Ca, Cl and H

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7
Q

which inorganic ion is most abundant outside cell

A

Na+

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8
Q

which inorganic ion is most abundant inside cell

A

k+

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9
Q

how is a voltage difference created

A

small excess of + or - charge on 2 sides of plasma membrane

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10
Q

membrane transport is mediated by?

A

2 classes of membrane proteins

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11
Q

what creates membrane potential

A

activity of membrane transport proteins

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12
Q

what transfers small organic molecules or inorganic ions?

A

transporters

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13
Q

how do substances pass by?

A

channels for pores and passes by diffusion

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14
Q

downhill movement

A

high conc to low conc (no driving force)

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15
Q

uphill movement

A

requires energy - active transport

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16
Q

what influences the passive transport of charged solutes?

A

conc gradient and membrane potential

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17
Q

for an uncharged molecule, movement is determined by

A

its conc gradient

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18
Q

for an charged molecule, movement is determined by

A

exert forces

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19
Q

osmosis is

A

diffusion and can modify shapes of cells

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20
Q

what is responsible for water reabsorption

A

aquaporin

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21
Q

what do passive transporters change

A

conformation to mediate transport

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22
Q

important example of passive transporter?

A

glucose transporter

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23
Q

how does glucose transporter work?

A

glucose binds the protein and changes the shape

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24
Q

active transport

A

movement of molecules against their conc

25
Q

active transporters

A

transmembrane proteins responsible for active transport

26
Q

what are the 3 types of proteins for active transport?

A

uniporter, symporter, antiporter

27
Q

uniporter?

A

one in one direction

28
Q

symporter

A

2 diff substances in same direction

29
Q

antiporter

A

2 diff substances in opposite directions

30
Q

what are coupled transporters

A

symporters and antiporters

31
Q

what are the 3 diff energy sources used in active transport

A

ATP, electrochemical gradient and light

32
Q

Ca2+ to ??

A

Ca2+

33
Q

Na+ to ???

A

energy

34
Q

what is a primary active transport

A

na+ transporter

35
Q

what is secondary active transporters

A

coupled transporters

36
Q

what are involved in glucose transfers

A

active and passive transporters

37
Q

how do large molecules enter and leave?

A

in is endocytosis
exp is exocytosis

38
Q

vesicle fusion

A

release of large and small molecules

39
Q

which molecules are too large to pass through

A

proteins, polysaccharides and nucleic acids

40
Q

what are the 3 types of endocytosis?

A

receptor-mediated

pinocytosis

phagocytosis

41
Q

how are electrical charges balanced outside of cell

A

Na+ ions by Cl- ions

42
Q

how are electrical charges balanced inside of cell

A

K+ by negative charges of organic molecules

43
Q

what creates a membrane potential

A

difference in concentration of inorganic ions

44
Q

how do inorganic ions move?

A

ion channels create openings for passive movement

45
Q

what are ion channels ?

A

narrow and highly selective

46
Q

what characteristics distinguish ion channels from pores?

A

ion selectivity and open/closure state

47
Q

which ion channels are gated

A

ligand-gated

voltage-gated

mechanically-gated

48
Q

what are ion channels responsible for?

A

electric signal generation and transmission in neurons

49
Q

what is recorded are changes in membrane potential

A

activities of neurons

50
Q

depolarized cell membranes

A

voltage Na+ open

51
Q

hyper polarized cell membranes

A

chemically gated K+

52
Q

what is action potential

A

rapid change

53
Q

what do action potentials do?

A

travel and jump along axons in 1 direction

54
Q

synapses

A

signal unique junctions

55
Q

synaptic cleft

A

post and presynaptic cells

56
Q

neurotransmitters receptors are ??

A

ligand-gated ion channels

57
Q

which gates are responsible for muscle contractions?

A

ligand

58
Q

mechanically-gated ion

A

channels in auditory hair cells allow us to hear