Mod. 1 Specific Cell stuff Flashcards
Which of the following is defined as an injurious, unstable agent that can cause cell death?
A) Tumors
B) Antioxidants
C) Free radicals
D) Antibodies
C) Free radicals
Rationale: Free radicals are unstable molecules that can cause oxidative damage to cells, potentially leading to cell death.
Cellular growth that no longer responds to normal regulatory processes, usually due to a mutation, is called:
A) Neoplasms
B) Antioxidants
C) Free radicals
D) Antibodies
A) Neoplasms
Rationale: Neoplasms (tumors) form when cells divide uncontrollably, often due to genetic mutations.
Which cellular adaptation is considered precancerous?
A) Dysplasia
B) Anaplasia
C) Hyperplasia
D) Metaplasia
A) Dysplasia
Rationale: Dysplasia is an abnormal change in cell size, shape, or organization, often considered a precancerous condition.
What is the purpose of cancer staging?
A) To determine the aggressiveness of tumor cells microscopically
B) To identify the genetic cause of the cancer
C) To describe the extent of cancer spread in the body
D) To measure the presence of tumor markers in the blood
To describe the extent of cancer spread in the body
Rationale: Staging assesses tumor size, lymph node involvement, and metastasis, guiding treatment options.
Which cancer screening guideline is recommended for early detection of colorectal cancer?
A) Yearly mammograms starting at age 40
B) Colonoscopy every 10 years starting at age 45-50
C) Monthly self-breast exams beginning at age 20
D) Pap smears every 3 years after age 21
B) Colonoscopy every 10 years starting at age 45-50
Rationale: Colonoscopies help detect early colorectal cancer and polyps, reducing mortality.
Which tumor cell marker is commonly used to monitor prostate cancer?
A) CA-125
B) CEA
C) PSA
D) AFP
C) PSA
Rationale: Prostate-Specific Antigen (PSA) is a biomarker used for prostate cancer screening and monitoring.
What is the 23rd pair of human chromosomes responsible for?
A) Coding for enzymes
B) Determining an individual’s sex
C) Regulating metabolic pathways
D) Expressing physical traits like eye color
B) Determining an individual’s sex
Rationale: The 23rd chromosome pair consists of sex chromosomes (XX for females, XY for males).
Which term describes a person’s observable traits, such as eye color and height?A) Karyotype
B) Phenotype
C) Genotype
D) Allele
B) Phenotype
Rationale: The phenotype is the outward expression of a person’s genetic makeup (genotype).
A patient inherits two identical alleles for a particular gene. This is an example of:
A) Heterozygosity
B) Homozygosity
C) Dominant inheritance
D) Recessive inheritance
B) Homozygosity
Rationale: Homozygous individuals inherit two identical copies of a gene, whereas heterozygous individuals inherit two different copies.
Which type of genetic disorder results from a mutation in a single gene?
A) Chromosomal disorder
B) Multifactorial disorder
C) Single-gene disorder
D) Environmental disorder
C) Single-gene disorder
Rationale: Single-gene disorders arise from mutations in a single gene, affecting function (e.g., cystic fibrosis, sickle cell disease).
Which pattern of inheritance requires only one mutated allele to cause disease?
A) Autosomal recessive
B) Autosomal dominant
C) X-linked recessive
D) Multifactorial inheritance
B) Autosomal dominant
Rationale: Autosomal dominant disorders require only one copy of a mutated allele to express the disease (e.g., Huntington’s disease, Marfan syndrome).