mnsr 42 Flashcards
– extends from the basement membrane to lumen forming desmosome-like contact w/ germ cells ( spermatogenic and primary speromcytes ) and plays a role in traslocating them
Sertoli cells
we have – types of germ cells and – types of somatic cells which are
- five germ cells
- 2 somatic : myoid smooth muscle cell and sertoli/sustecular cells
— forms tight junctions between each other ( blood-testis barrier ) , dividing the intercellular spaces into basal compartments contains —– and an intecullar adluminal compartment which contains —–
- Sertoli cells ( to prevent the protein and antibodies to be in contact w/ germ cells and less risk of autoimmune reactions )
- speromtogia
- primary spermatocytes
the primary spermatocyte enter — in the ad luminal compartment to produce — and —
- mioetic
- secondary spermatocyte and spermatids
—- involves cytoplasmic remodelling of each spermatids , occurs in close contact with — and takes place in the deep —- and no — takes place
- speriotegneis
-Sertoli cells - adluminal compartments
- no cell division
– is the specialised form of meiotic division which leads to devlopment of mature spermartoza in males
spermatogenesis
steps of speriotogensis :
1- the nuclease condenses into —–
and the Golgi apparatus and associated vesicles now migrate to the — where they develop —
2- the 2 — will migrate to the position — of the nucleas and form — , one centriole will form – in the centre of the —
3- the mitochondria asseblms into – around the upper region of the tail called — , most organelle are left in the residual cytoplasm in the adluminal crypt and the mature sperotozaon ( varies in size ) will depart to the —
- dark heterochromatin
- nucleas
- acrosome
- centrioles
- opposite
- acrosome
- axoneme
- sperm tail
- helix
- middle piece
- lumen
— with acrosome covering the nuclear material
– divided into 3 parts which are —-
the middle piece has — one in the — and the other gives rise to —-
all part of the spermatozoon are covered with —
- head
- tail ( middle which is occupied by the helix of mitochondria , principle which is covered by axial filament , end piece )
- 2 centrioles
- base of the nucleus
- axonme
- plasma membrane
the oogina divides – to produce — so that at birth all germ cells are —
after – month of the embryonic development the number of germ cells — sharply so most oogina — leaving —-
remaining oogina will divide — and miotic prophase is intitaed from the —
- mitotic
- primary oocyte
- oocytes
- 7th month
- die
- 1/2 million at birth
- first meiotic disvion
- 3rd month
on penetration of the egg by the spermteozan the — will resume and produces —
- 2nd miotic divisoon
- large ova and 2nd polar body ( the first polar body itself may divide to 3 polar bodies )
primary oocyte produces — with nearly all cytoplasm and —- unlike the 4 spermatozoa produced by primary spermatocyte
single ova , 2 or 3 polar bodies
fertilisation: involves the genetic material of haploid soerm and haploid oocyte emerging into a single diploid cell
1- the gelatinous remains of the membrane granulasa of the clumus oophuris is called —
2- the inside is glycoprotein called —
3- the fluid filled — and the cell plasma membrane
4- the perivitelline space contains the —
5- inside of the cell membrane is — or —
- corona radiata
- zona pelludicda
- pervitaline space
- first polar body
- yolky Vitellius or ooplasm
immediate fertalization can be done bc of — which refers to the result of removal of the glycoprotein coat from the sperm cell membrane by the enzymes which results in;
- capacitation
1- changes in the area of the acrosomal cap so acrosome reaction can be possible as removal of chelstrol and proteins
2- hyperactivity of the spermtozan as rhythm of tails and whiplash
— occurs in the fallopian tube and results in the realises of hyaloridnase and typrisn-like enzyme called –
- acrosome reaction
- acrosin
