Mixed 4

Question 1

Characteristics of Acute Transplant Rejection

Answer 1

Weeks to months

Dense interstitial lymphocytic (T-lymph) infiltrate on biopsy

Question 2

Primary congenital defect that leads to a cascade of further malformations

Answer 2

Sequence

Eg. Pierre Robin sequence: hypoplasia of mandibular prominence ➡️ micrognatia, displaced tongue, U-shaped cleft palate

Question 3

Hematologic and cardiovascular physiological changes of pregnancy

Answer 3

⬆️ ⬆️ plasma volume
⬇️ SVR
⬆️ HR and CO
⬆️ RBC
⬇️ Hb concentration (dilutional anemia)
⬆️ prothrombotic coagulation factors

Question 4

Potent long acting opiate agonist used for withdrawal and maintenance tx for opioid use disorder. Reduces cravings.

Answer 4

Methadone

Question 5

Insulin-dependent glucose transporter found in adipose tissue and striated muscle.
What kind of transport is it?

Answer 5

GLUT-4.

Facilitated diffusion, carried mediated transport.