Mixed 29

Question 1

Mechanism of action of Rasburicase

Answer 1

Recombinant uricase (urate oxidase), that catalyzes metabolism of uric acido to allantoin (more soluble purine metabolite)

Question 2

Classic characteristics of Edwards syndrome

Answer 2

Trisomy 18. Prominent occiput, Rocker-bottom feet, Clenched fists with overlapping fingers, low-set ears, micrognathia, , congenital heart disease.

Question 3

Incomplete fusion of the urethral folds in males, producing an abnormal opening of the urethra along the ventral shaft of the penis

Answer 3

Hypospadias

Question 4

Type of MCH expressed on surface of APC and presents antigensto T cells

Answer 4

MCH II

Question 5

Infection of 1 cell by 2 different segmented viruses that leads to RNA segment reassortment

Answer 5

Genetic/antigenig shift

Question 6

Results from a point mutation tha causes valine to substitute for glutamic acid in the sixth position of the b-globin chain of Hb

Answer 6

Sickle cell anemia