Mixed 28 Flashcards
Most highly oxigenated blood structure in the fetus
Umbilical vein, which empies in the IVC
Familial Alzheimer disease genetic associations
Early Alz: mutations of APP, presenilin 1 and presenilin 2
Late Alz: ApoE4 genotype
Pathogenesis and features of Hyperacute transplant rejection
Pre-existing recipient Antibodies vs donor (graft) antigens.
Within minutes to hours
Arterial fibrinoid necrosis and capillary thrombotic occlusion of graft vessels
Recurrent and unexpected panic attacks, abrupt surge of anxiety and distressing cardiopulmonary/neurologic symptoms. Associated with agoraphobia
Panic disorder
Classic findings in cutaneous leishmaniasis
Intracellular protozoa: rod shaped cytoplasmatic kinetoplasts.
Transmitted by sandfly bite
Chronic pinkish papulae that ulcerates
Enzyme that catalizes the rate-limiting step in heme syntesis that needs B6 vit as cofactor
Delta-aminolevulinic acid synthase
How Isoniazid leads to sideroblastic anemia
Inhibits activation of B6, needed for heme synthesis
Formula for cumulative incidence
new cases in specific period of time / # people at risk at the begining of that period
Disease found in severe ill patients that presents with low T3 and normal TSH and T4 due ↓ conversion of T3 to T4 in peropheral tissues
Eutyroid sick syndrome or low T3 syndrome
Cortisol and inflammatory cytokines inhibit 5’-deiodinase
Clinical presentation of Median (C5-T1) nerve injury
Loss of wrist flexion, flexion of lateral fingers, thumb opposition.
Loss of sensation over thenar eminence and lateral 3 1/2 fingers with proximal lesion.
Ape hand and Pope’s blessing
These drugs protect against destruction by beta-lactamase if given in combination with penicillins
Beta-lactamase inhibitors: Clavulanic acid, Sulbactam and Tazobactam
