Mixed 30

Question 1

Stain used for mitochondrial myopathies

Answer 1

Gomori trichrome stain

Question 2

Type of inheritance for mitochrondrial diseases

Answer 2

Maternal inheritance

Question 3

Fungal microorganism that at 37° forms a true hyphae from the yeast, called germ tube

Answer 3

Candida albicans

Question 4

Anomaly of midgut rotation that leads to small bowel clumped on the right side, with formation of fibrous Ladd bands

Answer 4

Malrotation. Can lead to volvulus and duodenal obstruction

Question 5

What it means shifting ODC to the right

Answer 5

↓Hb affinity for O2 → facilitates unloadign O2 to tissue)

Question 6

What it means shifting ODC to the left

Answer 6

↓ O2 unloading to tissue

Renal hypoxia → ↑ EPO synthesis

Question 7

How does carbon monoxide lead to hypoxia

Answer 7

CO binds to heme iron with much higher affinity than O2 (competitive binding).
↓ % O2 saturation of Hb

Question 8

Proteins that stimulate neutrophil migration to sites of infection (chemotactic agents)

Answer 8

Leukotriene B4, C5a, IL-8

Question 9

Mechanism of action of Benzodiazepines

Answer 9

Enhace the effect of GABA at GABA A receptor, leading to increased chloride influx and suppression of action potential firing