Mixed 27

Question 1

Classic characteristics of a complete hydatiform mole

Answer 1

Empty ovum fertilized by haploid sperm → 46,XX; 46, XY (less commonly)
Pelvic pain, vaginal bleeding, uterus larger than expected, ↑↑↑ hCG
Usg: multiple cystic areas (snowstorm pattern)
No fetal parts

Question 2

Allergic contact dermatitis type of hypersensitiviy reaction and type of immune cells involved

Answer 2

Type IV (delayed, cell-mediated type)
Main effector cells: CD8+

Question 3

X-linked recessive disorder. Causes hemolytic anemia and jaundice secondary to ↑ oxidative stress due to lack of NADPH. Heinz bodies and bite cells

Answer 3

Glucose-6-phosphate dehydrogenase deficiency

Question 4

Patients with Polycystic ovary syndrome are in risk of developing which carcinoma?

Answer 4

Endometrial hyperplasia/adenocarcinoma

Question 5

Cluster A personality disorder characterized by pervasive distrust, suspiciousness, hypervigilance, cynical view of the world

Answer 5

Paranoid disorder

Question 6

Which agent causes the most common cause of sporadic encephalitis, located in the temporal lobe, and presents as altered mental status, seizures, aphasia

Answer 6

Herpes simplex virus-1

Question 7

Fatal delayed hypersensitivity reaction, occurs 2-8 weeks after exposure to high risk drugs (allopurinol, anticonvulsants, sulfas, antibiotics), presents with fever, lymphadenopathy, facial edema, skin rash, eosinophilia

Answer 7

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome