MITOSIS AND MEOSIS Flashcards
“the fundamental biological variant is DNA”
Jacques Monod
In prokaryotes, cell division can be observed through?
In the eukaryotes, the cell cycle consists of two distinct phases:?
Binary fission
Interphase and mitotic phase
Series of events that occur in a cell to prepare cell division and to produce two new daughter cell
Cell cycle
Phases of cell cycle
Interphase and m-phase
Is the longest phase of the cell cycle process and is also known as the resting phase.
But it is metabolically active
Interphase
The cell increases in size, proteinsynthesis also occurs enable the cell to increase the amount of cytosol
G1 (Gap1 phase/ growth 1 phase)
Longest and the most essential stage of the interphase. Due to the complexity of the replication of the genetic material which results 5o the duplication of DNA
Synthesis phase
Final stage where the cell prepares itself for cell division and ensures that DNA replication completes
G2 (Gap2 or growth 2 phase)
Verify whether all the cellular activities are accurately completed at each stage
Cell cycle checkpoint
G1 checkpoints checks…
Cell’s size
Nutrients
DNA integrity
Molecular signals
Does the cell increase its size or large enough for cell division?
Cell’s size
” have enough reserve energy and nutrients for cell division
Nutrients
Is any part of the DNA damaged?
DNA integrity
” cell receives growth factors and other signals from neighboring cell
Molecular signals
Cell does not comply with the following factors
G-0 phase called resting state
G2 checkpoints checks…
DNA integrity
DNA replication
DNA replication completed in the s phase
DNA replication
If there is an error
Pause
It is the self destruction mechanism of the cell to ensure that the damaged DNA is not passed
Apoptosis/ cell death
Occur at the metaphase stage of mitosis. Checks whether all chromosomes are properly attached to the spindle fiber
Metaphase cp or spindle cp
Result of unregulated process of the cell cycle due to the breakdown of the mechanism
Cancer
Genes that cause the cell to become cancerous
Oncogenes
Are normal genes that help cells to grow
Proto oncogenes
Healthy normal genes that slowdown cell division, repair mistakes and also cell apop6
Tumor suppressor genes