Mitosis Flashcards

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1
Q

Prophrase

A

Chromosome condense (thicker/shorter)
= 2 sister chromatids, joined by centromeres
-nuclear envelope breaks down
-centrioles begin to pull apart move to opposite poles forming the spindle

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2
Q

Metaphrase

A

Chromosomes align along the equator of the cell

-spindle fibre attach to chromosome by centromeres

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3
Q

Anaphase

A

Chromatids from each pair are pulled, centromeres first towards opposite poles of the cell
Spindle fibre contract —> pull chromatids to opposite poles of the cell by the overlapping fibre contract and cause the movement of the chromatids supplied by ATP

Centromeres divides

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4
Q

Telephrase (two)

A

Chromosomes uncoil (longer/thinner) and separate becoming less dense

Nuclear envelope reforms = 2 nuclei

Spindle fibres & centrioles break down

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5
Q

Interphrase

A

Growing
Replicating DNA
Carry out normal cellular activities

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6
Q

G1

A
PREPARATION 
-organelle replicates
- increase cell size
-protein synthesis
—> respiration 

A signal is received telling the cells to divide again

This phrase of the interphase stage of the cell cycle is called the S phrase (synthesis of DNA) (relatively short)
Chromosomes replicate and become doubled stranded chromatids

  • cells make the RNA, enzymes and other proteins required for growth during the G1 phase
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7
Q

G2

A

The cell continues to grow and the new DNA that has been synthesised is checked and any error are usually repaired

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8
Q

What makes up interphase

A

G1+ S+ G2

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9
Q

Mitosis

A

Nucleus is actively dividing

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10
Q

Cytokinesis

A

New cell divides in the cytoplasm

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11
Q

Checkpoints

A

G1 checkpoint - cell size? DNA damage?

If not then goes into G0 ( cell leaves the cell cycle)

G2 checkpoint - DNA replication error

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12
Q

What happens in G0

A

Differentiate, (muscle cell)
die,
enter senescence (where they stop dividing) (ageing)

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13
Q

Why does mitosis happen

A

Repair
Growth
Asexual reproduction

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