Mitochondria Flashcards
how many membranes does the mitochondria
two : inner/outer
what does the outer mitochondrial membrane contain
many enzymes with diverse metabolic function
describe the pores on the outside of the OMM
large channels. when open membrane is freely permeable (not completely but highly)
describe the inner mitochondrial membrane
-high protein-lipid ratio (3-1)
-double layered folds (Christae)
(proof that it come from original bacteria)
-rich in phospholipid (cardiolipin)
what is cristae
double folds in the inner mitochondrial membrane
- increases surface area
- contains machinery for aerobic respiration, ATP formation
what is cardiolipin
the phospholipid only found in inner membrane of mitochondria and bacteria
describe the matrixes of the mitochondria
-high in protein (makes gel-like consistency)
-contains mitochondria ribosomes and DNA
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what does mitochondrial dna do
encodes polypeptides that are integrates into IMM, ribosomes, and tRNA
what is oxidative phosphorylation
ATP synthesis in the mitochondria
what are the two steps of oxidative phosphorylation
1) electron transport and proton pumping (generates an electrochemical gradient)
2) proton (H+) movement down electrochemical gradient powers the ATP synthesis
what range is the pH of the ingtermembrane
low because of the high levels of H+
high energy ____ pass from ____ (NADH, FADH2) in the matrix to electron carriers in the ____
high energy electrons pass from coenzymes in the matrix to electron carriers in the inter membrane
series of e- carriers (respiratory enzyme complexes 1,2,3,4)=?
electron-transport chain (etc)
what is the energy transfer at each complex used for
energy transfer at each complex is used to pump protons (h+) from the matrix to inter membrane space
low energy electrons are tranferred to the acceptor, what is produced
h2o