Miscellaneous lipid-lowering medications

Question 1

Answer 1

Question 2

Answer 2

Question 3

Answer 3

Question 4

Answer 4

Question 5

Answer 5

Hyperuricemia

Question 6

Answer 6

Omega 3 fatty acids

Question 7

Answer 7

Degradation of low-density lipoprotein receptors (LDL-R) on liver cells

Question 8

Answer 8

Inhibition of intestinal cholesterol absortion

Question 9

A 45 year old man comes to the office for the evaluation of his abnormal lipid panel and is currently asyntomatic. Past medical history is significant for type II diabetes mellitus, and an episode of pancreatitis 6 months ago. Current medications include metformin and atorvastatin. Family history is significant for myocardial infarction in father and chronic renal failure in mother. He smokes a pack of cigarettes daily, drinks 2 glasses of beer on weekends and does not use illicit drugs. Vitals are within normal limits. His BMI is 33.5 kg/m2. Physical examination is noncontributory. Fasting laboratory workup at today´s visit is shown below. the patient is recommended to maintain a low-fat diet to reduce weight, and fenofibrate is added to his medication regime. Which of the following best describes the effect of fenofibrate therapy on serum LDL, HDL and TGs?

Answer 9

• Low density lipoproteins (LDL) ↓
• High density lipoproteins (HDL) ↑
• Triglycerides (TGs) ↓↓↓

Question 10

Answer 10

Cholestyramine

Question 11

Answer 11

Administer aspirin 30 minutes before taking her medication