Miscellaneous Drugs Flashcards
Aspirine (Acetylsalicylic acid)
Nonselctive, irreversible inhibitor of COX1 and COX2
Levalbuterol
Short acting beta-2 agonist
Sulfsalazine
Anti-inflammatory: 5-aminosalicyclic acid and sulfapyridine
Warfarin and Pregnancy
Use heparin instead. Fetal death is common
Desloratadine
Second Gen Antihistamine
Metoclopramide
Prokinetic Agent. D2 antagonistic Ach release.
Diphenhydramine
First Gen Antihistamine
Zileuton
Leukotriene Inhibitors. Inhibits 5-lipooxygenase (leukotriene synthesis).
Dimenhydrinate (Dramamine)
First Gen Antihistamine
Simethicone (gasX)
Coats gas and dissipates it
Asthma step wise therapy
1.) rescue inhaler: beta 2 agonist 2.) inhaled steroid (cromolyn for children) 3.) Leukotriene inhibitor 4.) Long acting beta agonist or another bronchodilator (ipratropium) Add oral steroid whenever needed
Indacaterol
Long acting beta-2 agonist. Given with a steroid.
Rabeprazole
PPI
Naproxen
NSAID. Non selective reversible inhibitor of COX1 and COX2
Phenytoin and pregnancy
Fetal hydantoin syndrome: growth retardation, mental deficiencies, abnormal genitalia, cardiac abnormalities. Most anticonvulsans are associated with these problems.
Prophylactic Migraine Drugs
Beta-blockers (propranolol), CCB (verapamil), Antidepressants (amitriptyline, fluoxetine), Clonidine, valproic acid, topiramate, botox, angiotensin II receptor blocker.
Certirizine
Second Gen Antihistamine
Lansoprazole
PPI
Bisacodyl
Laxative. Mucosal Agent.
Sucralfate
Cytoprotective. Polymerizes to provide a protective barrier cells in ulcers base
Certrolizumab
DMARD. TNFalpha binder. Human IgG1.
Mycophenolate mofetil (cellcept)
DMARD. Inhibits lymphocyte purine synthesis
Tofacitinib
DMARD. Inhibits JAK1 and JAK3. Used for Ra that is intolerant to methotrexate.
Golimumab
DMARD. TNFalpha binder. Human IgG1.