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Pharmacology > Anit-arrhythmics > Flashcards

Anit-arrhythmics Flashcards

1
Q

Quinidine (cardioquin)

A

Class 1A

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2
Q

Quinidine (cardioquin) MOA

A

Binds Activated sodium channels

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3
Q

Quinidine (cardioquin) Effects

A

Broad spectrum. Artial and ventricular arrhythmias

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4
Q

Quinidine (cardioquin) Side effects

A

Torsades due to QT prolongation. Quinidine syncope. Diarrhea.

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5
Q

Procainamide (pronestyl)

A

Class 1A

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6
Q

Procainamide (pronestyl) Side Effects

A

Lupus

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7
Q

Lidocaine (xylocaine)

A

Class 1B

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8
Q

Lidocaine (xylocaine) MOA

A

Binds inactivated sodium channels

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9
Q

DOC for ACUTE ventricular arrhythmia

A

Lidocaine (xylocaine)

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10
Q

Lidocaine (xylocaine) Effects

A

Ventricular arrhythmias with the least negative inotrope effects so useful in CHF

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11
Q

Flecainide (tambocor)

A

Class 1C

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12
Q

Flecainide (tambocor) MOA

A

Blocks all sodium channels. Last Ditch effort.

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13
Q

Flecainide (tambocor) adverse effects

A

pro arrhythmic

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14
Q

Beta Blockers

A

Class II

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15
Q

Esmolol Indications

A

IV only treatment of Acute PSVTs

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16
Q

Amiodarone (cordarone)

A

Class III

17
Q

Amiodarone (cordarone) MOA

A

Blockes potassium channels. Also blocks sodium channels. Acts as a beta blocker, alpha blocker and CCB

18
Q

DOC for ventricular arrhytmias

A

Amiodarone (cordarone). Chronic or Acute.

19
Q

Amiodarone (cordarone) Indications

A

DOC for ventricular arrhythmia but also useful in atrial arrhythmias

20
Q

Amiodarone (cordarone) Adverse effects

A

Prolongs QT but without torsades. Pulmonary fibrosis. Thyroid dysfunction.

21
Q

Sotalol (betapace)

A

Class III

22
Q

Sotalol (betapace) MOA

A

Potassium channel and beta blocker.

23
Q

Sotalol (betapace) Adverse effects

A

Torsades

24
Q

Calcium Channel Blockers

A

Class IV. Verapamil and Dilitazem

25
Q

CCB indications

A

PSVT. Only effective in the atria!

26
Q

CCB adverse effects

A

Constipation

27
Q

Adenosine

A

Increased potassium and calcium permeability. Hyperpolarizes the cell. IV only.

28
Q

DOC for acute PSVT

A

Adenosine

29
Q

Acute PSVT treatment

A

Adenosine, Esmolol, CCB (IV)

30
Q

Chronic PSVT Treatment

A

Beta-blocers and CCB (oral)

31
Q

DOC for torsades

A

Magnesium

32
Q

Potassium MOA

A

Hyperpolarizes the cell

Pharmacology (24 decks)

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