Anit-arrhythmics Flashcards
Quinidine (cardioquin)
Class 1A
Quinidine (cardioquin) MOA
Binds Activated sodium channels
Quinidine (cardioquin) Effects
Broad spectrum. Artial and ventricular arrhythmias
Quinidine (cardioquin) Side effects
Torsades due to QT prolongation. Quinidine syncope. Diarrhea.
Procainamide (pronestyl)
Class 1A
Procainamide (pronestyl) Side Effects
Lupus
Lidocaine (xylocaine)
Class 1B
Lidocaine (xylocaine) MOA
Binds inactivated sodium channels
DOC for ACUTE ventricular arrhythmia
Lidocaine (xylocaine)
Lidocaine (xylocaine) Effects
Ventricular arrhythmias with the least negative inotrope effects so useful in CHF
Flecainide (tambocor)
Class 1C
Flecainide (tambocor) MOA
Blocks all sodium channels. Last Ditch effort.
Flecainide (tambocor) adverse effects
pro arrhythmic
Beta Blockers
Class II
Esmolol Indications
IV only treatment of Acute PSVTs
Amiodarone (cordarone)
Class III
Amiodarone (cordarone) MOA
Blockes potassium channels. Also blocks sodium channels. Acts as a beta blocker, alpha blocker and CCB
DOC for ventricular arrhytmias
Amiodarone (cordarone). Chronic or Acute.
Amiodarone (cordarone) Indications
DOC for ventricular arrhythmia but also useful in atrial arrhythmias
Amiodarone (cordarone) Adverse effects
Prolongs QT but without torsades. Pulmonary fibrosis. Thyroid dysfunction.
Sotalol (betapace)
Class III
Sotalol (betapace) MOA
Potassium channel and beta blocker.
Sotalol (betapace) Adverse effects
Torsades
Calcium Channel Blockers
Class IV. Verapamil and Dilitazem
