Midterm | Skeletal System Flashcards
TWO DIVISION of skeletal system
AXIAL
APPENDICULAR
Differentiate ligament, tendon, and joints
Joints (Bone to bone): where bones meet; acts as a hinge which helps body part move somothly
Ligaments (bone to bone): hold the bones together at the joints; stabilize joints
Tendons (bone to muscle): connect muscles to bones, allowing movement.
Kyphosis vs Lordosis
Kyphhosis: Outward curve
Lordosis: Ineward curve
Pain in the joints
ARTHRALGIA
Disease of the joints
ATHROPATHY
Displacement of the bone; dislocation
LUXATION
Partial displacement of a bone from its joint ; partial dislocation
SUBLUXATION
Twisting of a joint, resulting in pain, swelling and injury to the ligaments
SPRAIN
SPRAIN vs STRAIN
Sprain: Injury to a ligament
Strain: Inury to tendons
Any break in a bone
FRACTURE
Commons FRACTURES
- COMMINUTED Fx
- COMPOUND Fx
- COMPRESSION Fx
- GREENSTICK Fx
- SIMPLE Fx
- IMPACTED Fx
Splintered / crushed bone
COMMINUTED Fx
What does COMMINUTED Fx affect?
Long bones
A break in the bone accompanied by an open wound in the skin
COMPOUND Fx
Other term for COMPOUND Fx
OPEN FRACTURE
A break in a bone resulting from compression, usually involves one or more vertebrae.
COMPRESSION Fx
Condition in which a bone is partially bent and partially broken, as when a bamboo breaks
GREENSTICK Fx
Patients commonly affected by GREENSTICK Fx
Patients 10years old or below
A break in a bone without an external wound (with no break in the skin)
SIMPLE Fx
Other term for SIMPLE Fx
CLOSED Fx
A break in a bone in which one fragment is wedged into the other
IMPACTED Fx
Inflammation of the joint
ARTHRITIS
How is arthritis formed?
Bones rub against each other, causing the inflammation
Inflammation of the joints caused by GOUT
GOUTY ARTHRITIS
Body part usually affected by GOUTY ARTHRITIS
Big toe
Gout is a disease involving abnormal —
uric acid metabolism
How is uric acid relevant to developing gout?
When the body breaks down certain foods, it creates a waste product called uric acid. This uric acid is normally flushed out of your body through pee. If the body makes too much uric acid, or it can’t get rid of enough of it, this can lead to uric acid building up in your blood. In gout, high levels of uric acid lead to the formation of urate crystals in the joints, causing inflammation and pain.
Chronic inflammatory disease characterized by destruction of articular cartilage and overgrowth of bone in the weight-bearing joints
OSTEOARTHRITIS
Other term for OSTEOARTHRITIS
OA or DJD (degenerative joint disease)
RHEUMATOID ARTHRITIS is characterized by?
Inflammation
pain
stiffness
eventually deformity of the affected joints due to inflammation of the synovial membrane
Inflammation of the bursae, usually occurring in association with arthritis
BURSITIS
Inflammation of the bone and bone marrow usually due to infection
OSTEOMYELITIS
Where are bone marrows located?
Long bones, spine, or vertebrae
Inflammation of the
periosteum, usually due to a blow to the bone
PERIOSTITIS
Inflammation of the synovial membrane, usually resulting from injury, infection or arthritis
SYNOVITIS
Most common inherited disorder affecting the skeletal system, which results in bone deformity and dwarfism
ACHONDROPLASIA
Other term for ACHONDROPLASIA
Short limb dwarfism
What results from ACHONDROPLASIA?
bone deformity and dwarfism
Chronic inflammatory disease of the spine characterized by fusion and loss of mobility of two or more vertebrae
ANKYLOSING SPONDYLITIS
OSTEOGENESIS IMPERFECTA (OI) is sometimes referred to as (1). It is quite a serious and rather rare (2) or (3) disease which can range from (4)
- brittle bone disease
- heritable
- congenital
- mild to severe
Congenital disorder characterized by malformation of the spine due to abnormal formation and joining of the vertebrae
SPINA BIFIDA
Condition characterized by damage to the cartilage of the kneecap, resulting in pain
CHONDROMALACIA PATELLAE
CHONDROMALACIA PATELLAE is most commonly found in —
adolescents
How is CHONDROMALACIA PATELLAE developed?
When the cartilage under the kneecap ad femur softens or deteriorates, leading to pain and discomfort in the knee joint.
Softening and weakening of the bones
OSTEOMALACIA
OSTEOMALACIA is usually due to?
vit D deficiency
In children, OSTEOMALACIA is known as —
RICKETS
Loss of calcium and bone
tissue, causing the bone to become porous, brittle and easily fractured
OSTEOPOROSIS
OSTEOPOROSIS is common in?
Most commonly seen in postmenopausal women
PAGET’S DISEASE is characterized by?
Weakened, thickened, deformed bones
PAGET’S DISEASE is common in?
Most commonly seen in middle aged and elderly adults
Varus vs Valgus
Varus: Distal part of a limb is angled inward, towards the midline of the body (distal part: more medial)
Valgus: Deformity where the affected body part bends outward or away from the midline of the body (distal part: more LATERAL)
Protrusion of a vertebral disk into the center of the vertebral column; irritating the spinal nerves and causing pain
HERNIATED DISK
Abnormal curvature of the vertebral column, eventually causing back pain, disk disease, or arthritis; often a congenital disease
SCOLIOSIS
Scoliosis can be a curvature towards the right (1) or towards the left (2)
- dextroscoliosis
- levoscoliosis
KYPHOSIS is an increased curvature of the (1) of the vertebral column, leading to a (2)
- thoracic region
- humpback posture
KYPHOSIS may be caused by —
arthritis
poor posture
osteomalacia
chronic
respiratory disease
CARPO
LORDOSIS is a (1) curvature of the
(2) of the vertebral column, leading to a (3)
- forward
- lumbar region
- swayback posture
LORDOSIS is usually caused by
Increased weight in the abdomen, as during pregnancy
(PHARMACEUTICAL FOR OSTEOPOROSIS) TWO BASIC CATEGORIES
- ANTIRESORPTIVE DRUGS
- ANABOLICS
How does ANTIRESORPTIVE DRUGS work?
Work by slowing the resorption of the breaking down part of the remodeling cycle
Examples of ANTIRESORPTIVE DRUGS
Bisphosphonates (alendronate,
ibandronate),
Calcitonin,
Estrogen/estrogen-progestin,
etc.
How does ANABOLICS work?
Work by stimulating the formation part of the remodeling process. More bone is formed than is taken away.
Antiresorptive drugs vs Anabolics
Antiresorptives: Slows down resorption of bone tissue; prevents bone loss
Anabolics: Stimulates formation of bone tissue; forms strogner and denser bones
PHARMACEUTICAL FOR ARTHRITIS)
1.NONSTEROIDAL ANTI-INFLAMMATORY DRUGS
2. ANALGESICS
3.CORTICOSTEROIDS
4.DISEASE MODIFYING ANTI-RHEUMATIC DRUGS (DMARDs)
NSAIDS vs Analgesics
NSAIDS: More on inflammatory response
Analgesics: More on pain relief
Blocks enzymes that produces inflammation and pain
NSAIDs
Examples of NSAIDs
a) Advil (ibuprofen)
b. Aleve (naproxen)
Blocks pain signals in the brain
Analgesics
Example of Analgesic
Acetaminophen
Slow acting medications that work behind the scenes to slow down progression of rheumatoid arthritis and reduce the risk of permanent joint damage
DISEASE MODIFYING ANTI-RHEUMATIC DRUGS (DMARDs)