Microbiology 20 - Neonatal and Childhood infection Flashcards

1
Q

What infections are currently screened for in pregnancy in the UK?

A

Hep B
HIV
Syphilis

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2
Q

What does TORCH stand for?

A
Toxoplasmosis
Other (syphilis, HIV, Hep B/C) 
Rubella
CMV
HSV
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3
Q

What effect can toxoplasmosis have on the neonate?

A

Deafness, low IQ and microcephaly

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4
Q

Recall the symptoms of congenital rubella syndrome

A
Cataracts
CV syndrome
Sensorineural deafness
Brain pathology
BLUEBERRY MUFFIN RASH
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5
Q

What is the cause of a ‘blueberry muffin rash’ and in which infection is it seen?

A

Extramedullary haematopoiesis

Congenital rubella syndrome

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6
Q

Recall the symptoms of congenital HSV infection

A

Nasty disseminated infection, causing:

  • Meningoencephalitis
  • Ulcers and skin problems
  • High mortality
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7
Q

What are the ‘big 3’ neonatal infections?

A

Listeria
E coli
Group B strep

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8
Q

Which neonatal infection could be described as ‘catalase negative, beta haemolytic’?

A

GBS

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9
Q

What is the most common cause of late-onset sepsis in neonates?

A

Coagulase negative staph

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10
Q

What is the first line treatment for late-onset neonatal sepsis?

A

Cefotaxime (this is brain-penetrative) and vancomycin (this is good for staph)

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