Microbiology 20 - Neonatal and Childhood infection Flashcards
What infections are currently screened for in pregnancy in the UK?
Hep B
HIV
Syphilis
What does TORCH stand for?
Toxoplasmosis Other (syphilis, HIV, Hep B/C) Rubella CMV HSV
What effect can toxoplasmosis have on the neonate?
Deafness, low IQ and microcephaly
Recall the symptoms of congenital rubella syndrome
Cataracts CV syndrome Sensorineural deafness Brain pathology BLUEBERRY MUFFIN RASH
What is the cause of a ‘blueberry muffin rash’ and in which infection is it seen?
Extramedullary haematopoiesis
Congenital rubella syndrome
Recall the symptoms of congenital HSV infection
Nasty disseminated infection, causing:
- Meningoencephalitis
- Ulcers and skin problems
- High mortality
What are the ‘big 3’ neonatal infections?
Listeria
E coli
Group B strep
Which neonatal infection could be described as ‘catalase negative, beta haemolytic’?
GBS
What is the most common cause of late-onset sepsis in neonates?
Coagulase negative staph
What is the first line treatment for late-onset neonatal sepsis?
Cefotaxime (this is brain-penetrative) and vancomycin (this is good for staph)