Microbiology 1 - Hospital acquired infection Flashcards
What if the most common disease caused by an HAI?
Hospital acquired pneumonia
What type of bacteria is c. difficile?
Gram pos spore-forming anaerobe
Name the toxins produced by c. difficile
Toxins A and B
What are the symptoms of C. difficile infection?
Diarrhoea
Colitis
Name 2 Antibiotics that are used to treat C. difficile?
Metronidazole
Vancomycin
What type of bacteria is vancomycin effective against?
Gram pos
What is the pathognemonic endoscope finding for C diff infection?
Columns of inflammatory exudate in colon lining
How should C diff infection be managed?
- Stop antibiotics
- Fluid + electrolyte resuscitation for patients with diarrhoea
- ORAL vancomycin/ metronidazole to combat C. diff
Other options (but are VERY ££££££) are fidaxomicin or bezlotoxumab OR faecal transfer
What are the most common causative pathogens in HAP?
S aureus
Klebsiella
Pseudomonas
Haemophilus
Which 3 antibiotics can predispose you to C diff infection?
Cephalosporin
Clindamycin
Ciprofloxacin