Microbiology 15 - Zoonoses Flashcards

1
Q

What are the key features of campylobacter food poisoning?

A

Bloating and cramps

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2
Q

What are the key features of salmonella infection?

A

Diarrhoea and vomiting

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3
Q

How can salmonella food poisoning be treated?

A

Supportive + ciprofloxacin

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4
Q

Which types of salmonella must always be treated, and with which can you wait to see if they will need treatment?

A

S. typhi/ paratyphi = always treat

Other types = watchful waiting

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5
Q

Bartonella is a zoonotic infection from which animal?

A

Kittens

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6
Q

What diseases can be caused by bartonella henselae?

A

Cat scratch disease/ baciliary angiomatosis (if immunocompromised)

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7
Q

How should cat scratch disease be treated?

A

Erythromycin + doxycycline

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8
Q

What are the signs of baciliary angiomatosis?

A

Skin papules and whacky LFTs

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9
Q

Toxoplasmosis is a zoonotic infection from which animal?

A

Cats

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10
Q

How is toxoplasmosis treated?

A

Spiramycin

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11
Q

What is the risk with toxoplasmosis infection in the immunocompromised?

A

That it will be reactivated, leading to progressive visual/ hearing/ motor/ cognitive impairment and seizures

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12
Q

What is the risk with toxoplasmosis infection in pregnancy?

A

Still birth

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13
Q

Where in the world is brucellosis most likely found?

A

Middle East

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14
Q

What are the symptoms of brucellosis?

A

Fever, back pain, orchitis, focal abscesses

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15
Q

What is the causative organism in Q fever?

A

Coxiella burnetti

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16
Q

How is coxiella burnetti transmitted to humans?

A

Unpasteurised milk

17
Q

What are the symptoms of Q fever?

A

It’s a flu-like illness

18
Q

What is the treatment for Q fever?

A

Doxycycline

19
Q

What are the causative organisms in rabies?

A

Lyssa viruses

20
Q

What are the symptoms of rat bite fever?

A

Fevers and polyarthralgia

21
Q

Hantovirus is transmitted to humans via contact with which type of animal?

A

Rats

22
Q

How can rite bite fever and hantovirus be differentiated clinically?

A

Rat bite fever = polyarthralgia

Hantovirus = myalgia

23
Q

Recall some general principles of investigating and treating zoonotic infections

A
  1. History is very important
  2. Investigation should involve relevant cultures
  3. Do serology in a targeted way - do not break the NHS budget!
  4. Pls don’t do PCR cause it costs a fortune
  5. Doxycycline is usually a good punt for treatment