Microbial diseases

Question 1

What are the two main categories that microbial diseases are distuingished by and the subcategories within them

Answer 1

Infectious- Chronic and acute

Aquired (but not infectious)-Chronic

Question 2

Lepracy is what kind of disease?

Answer 2

Infectious chronic

Question 3

Meningitis is what kind of disease?

Answer 3

Infectious acute

Question 4

unulcerated collitis is what kind of disease?

Answer 4

Acquired but not infectious chronic

Question 5

What are the routes of infection?

Answer 5

-Gastrointestinal tract
-Respiratory tract
-Wounds or abrasions in mucous membranes or skin
-Genitourinary tract
Parenteral (through bloodstream, insect bites, stab wounds…)
-Vertical transmission

Question 6

What is one of our largest barriers for infection?

Answer 6

Skin- Keratin, sebum, langerham cells

Question 7

How is the mucous membrane of the intestine a good barrier to infection?

Answer 7

• Destroys pathogens

- Cilia remove microbes from lungs

Question 8

How do tight junctions work?

Answer 8

Intercollated series of glycoproteins, producing a barrier to pathogens

Question 9

Gut-associated lymphoid tissue (GALT) is critical for what?

Answer 9

Specialised M cells that take microbes and kill them within tonsils, adenoids and payer patches

Question 10

What are some chemical barriers to infection?

Answer 10

• Defensins-cationic peptides
• 29-47 amino acids
• Destroy microbes cytoplasmic membrane
• Ppetide binds negatively charged oouter membrane
• Then oulled into the cytoplasmic membrane