Micro Pharm Flashcards
Treat MSSA with?
Penicillinase Resistant Penicillin ( methicillin, dicloxacillin, nafcillin)
Community Acquired MRSA
Clindamycin, TMP/SMX, DOXY
Hospital Acquired MRSA
Vanc + or - Gent + or - Rit
Strep Pyogenes
Penicillin
C. perfringens
Penicillin
Penicillinase Resistant Penicillin ( methicillin, dicloxacillin, nafcillin) Mech of Action
Cell wall inhibitor, -cidal
Penicillinase Resistant Penicillin ( methicillin, dicloxacillin, nafcillin) Agent Fate excretion
Oral (diclox), parenteral (naf), active tubular secretion (short acting), metabolism
Penicillinase Resistant Penicillin ( methicillin, dicloxacillin, nafcillin) side effects
allergy, diarrhea
Penicillinase Resistant Penicillin ( methicillin, dicloxacillin, nafcillin) Drug Interactions
Not significant
Penicillin MOA
cell wall inhibitor, -cidal, fast acting
Penicillin Agent fate excretion
Oral, parenteral, active tubular (short acting)
Penicillin Adverse drug interactions
ALLERY, K IV prep
Penicillin Drug interactions
No significant
Cephlosporin (cephalexin, cefazolin, ceftriaxone) MOA
cell wall, -cidal
Cephlosporin (cephalexin, cefazolin, ceftriaxone) Agent fate excretion
oral, parenteral, active tubular, PROTEIN BOUND, metabolized
Cephlosporin (cephalexin, cefazolin, ceftriaxone) ADR
allergic, cholycystitis, kenicterus, bleeding
Cephlosporin (cephalexin, cefazolin, ceftriaxone) Drug interactions
Not significant
Cephlosporin (cephalexin, cefazolin, ceftriaxone) GOOD FACT
CEFTAZIDIME good against P AERUGENOSA
Doxycyline MOA
30s subunit RNA, -static
Doxycyline Agent Fate excretion
oral, parenteral, metabolism
Doxycyline ADR
GI (impt to know), diarrhea (C diff), BONES AND TEETH ( CONTRA IN 8-12 Y/O), Infections
Doxycyline Drug interactions
-Dont use -cidal and -static together, milk (Ca products)
