MICRO EXAM #3 Flashcards
what is fast reproducing
S. pneumonia
what happens to cilia in S. pneumonia
paralyzed then mucus travel down and carry bacteria
S. pneumonia starts up after
flu (secondary infection)`
what did Beijerinick say the causative agent for TMD
contagious living fluid
who renamed nuclien to nucleotide
levene
who found incorrect theory of tetranuteotide
levene
chargoff did what
proved Levene wrong
what lead to virology
Mayer and beirjerinick work
founder of biology
beijernick
what did Mayer think was causing TMD
toxin or bacteria
who discovered double helix structure
Watson and crick
cause of dysentary
shigella dysenteria
what can make shiga toxin
shigella dysenteria
who works with dysentary patients
Felix d’herrelle
what does Felix d’herrelle want to study
why some patients recover from dysentary and some dont
what study did bacteriophage come into play
study of dysentary
bacteriophage
a virus that parasites a bacterium by infecting it and reproducing inside it.
what can bacteriophage play a critical role in
human disease
plaque
holes that form on petri-plate covered with bacteria, over time, the holes will grow larger until bacteria is destroyed.
bacteriophage theory
therapeutic use of lytic bacteriophage to treat pathogenic infections
pyro (bacteriophage theory)
throat
Staphy ((bacteriophage theory)
drink
rhino ((bacteriophage theory)
nasal spray
bacteriophage theory vs antibiotic theory
bacteria can develop resistance to phages, phages will evolve too. easier to develop new bacteriophages than antibiotics
characteristics of viruses
- nucleic acid (DNA, RNA) 2. protein coat 3. all virus inject nucleic acid into host cells 4. host cells are taken over to make new viruses
head of virus
capsid, nuclei (dna, rna)
tail of virus
sheath, plug, tail fibers
what makes the phosphate-deoxyribose backbone
sugar and phosphate
conjugation
physical contact,
what is least common
transformation
what goes form same genus and species
transformation
bacteria are well known for something called
horizontal gene transfer
bacteria can pass genes to
offspring, neighboring bacteria, or even not same genus or species
exchange of genes from one bacterium to another
transformation and conjugation
exchange of genes from virus to bacterium
transduction
transformation
donor bacteria chromosome, bacteria cell wall opens, reciepeint bacterium needs DNA binding protein
conjugation
two bacteria exchange small pieces of DNA through mating tubes. long mating tube called fimbrae
plasmid
circular dna
conjugation dan replicates by
rolling circle mechanism
what often give antibiotic resistance to organisms
plasmid
antibiotic
molecules that cause damage to bacteria
what was penicillin originally made by
molds
what makes antibiotics
molds
plasmid is
extrachromosomal DNA
chromosomes
thread like structure of nucleic acids and protein found in the nucleus
what does chromosomes do
binds and condenses DNA molecule to prevent it from becoming unmanageable tangle
4 ways bacteria become antibiotic resistant
- efflux pump: transfer protein leads antibiotics out 2. impermeability: antibiotic cant cant though at all (structure of cell wall) 3: modified target: modifies ribosome by slight protein change 4: destruction: production of new enzyme
what bacteria does modified target very often
mycobacterium tuberculosis
bacteria become antibiotic resistant #4
s. aures or penicillin
in order for microbes to become resistant, two things must happen
variations must be heritable, variations must have potential to affect microbes fitness
new antibiotic resistance mechanism that is not heritable
s. p can serve and grow in antibiotic if there is enough antibiotic-resistant bacteria around it
what is required in transduction
bacteriophage and 2 bacteria
does 2nd phage have its own DNA
NO because recipient isn’t killed and use bacterium DNA as their own
human genes only transfer their genes
vertically
biofilm breakaway
killer bacteriophage inserts this gene into dna of biolfim producing bacteria. new gene codes for breakaway enzyme and it cannot be turned off . rapidly stops biofilm production and antibodies come in and destroy bacteria
in 1950 what was created
cdc in atlanta GA
why was cdc created
to combat malaria
cdc helped by
vaccine research, polio research, bacteriophage research, cancer research, investment into electron microscope
4 things Watson and crick new
- building blocks of dna were nucleotides, 2.each nucleotide has one base 3. bases are bonded too sugars. 4. sugars are bonded to phosphate group
what causes thrush
ph level drops and bacteria die, fungi and yeast grow
Candida albicans
ORAL yeast infection, thrush, vaginitis
what cause rough s. pneumonia to become smooth
transforming principle of dam
group a can cause
strep throat or secondary infections
what is resistant to many medications
staph. aureus
MRSA
staph. aureus Constantine mutating and becoming resistant
shiva toxin in e. coli
STEC
found in fresh or sea water
vibrio choleae