micro Flashcards
toxins acting by EF2
coryn. diptheria
pseudomonas(exotoxin A)
volutin granules aka(2)
babes ernst/metachromatic granules
of coryn diptheria
granules of coryn m/o
contains
polymetaphosphates
act as enzymes
toxin
toxin acting by ADP ribosylation
corynaebact.diptheria
elek gel ppt test for which toxin
coryn.diptheria
shick’s skin test for
coryn.diptheria
A and B units of exotoxin
A=action
B=binding
toxin acting by 60S inhibition
shiga toxin
shiga like/vero like=EHEC
hemolytic uremic syndrome by?
strain?
EHEC
O157:H7
triad
1 microangiopathic hemolytic anemia
2 thrombocytopenia
3 renal failure
hemolytic uremic syndrome
O157:H7 EHEC does not fremnt?
sorbitol
O157:H7 grows on
McConkey agar
Lactose
cholera toxin binds to
GM1ganglioside receptor
toxin working on zonaoccludens
cholera toxin
cholera toxin which sub unit binds to gm1 ganglioside recptor
alpha
hemorrhagic diarrhea/dysemtry is caused by which toxins?
class?
shiga toxin/ EHEC(SLT/VLT)
60s inhibitors
which toxins act by cAMP
cholera
anthrax
LT(ETEC=heat labile)
pertussis
whooping cough on inspiration
infants=apnea
by?
pertussis
toxin acting by cGMP
ETEC=ST(heat stable)
toxin causing spastic paralysis
tetanus
strychnine
travellars diarrhea by
ETEC
toxin acting by inhibiting SNARE
GABA/glycine
tetanus
toxin inhibiting pre synaptic release of NT
tetanus
botulinum
toxin inhibiting post synaptic excitation
strychnine
toxin inhibiting Ach release
botulinum
rhisus sardonicus/lock jaw
seen in
tetanus/strychnine?
tetanus
posturing seen in tetanus/strychnine?
both
preformed botul.toxin seen in
canned food
spores of botulinum seen in
honey
wounds
honey causes?in infants
descending flaccid paralysis
superantigen sits over ? in MHC complex
antigen site
superantigen causes?
toxic shock syndrome
cause shock
inc cytokines
fever
bacteria acting by superantigen
staph
strep
history of retained? in toxic shock syndrome(2)
tampons
nasal gauge in epistaxis
catalase positive organisms?(7)
staph aureus
Serratia
pseudomonas
aspergillus
cryptococcus
candida
enterobacter
enterobacter class?
gram negative
facultative
anaerobe
Fast Lactose fermenting
pseudohemoptysis causing prodogesin produced by?
serratia
pigment producing catalase positive bacteria
staph aureus=golden yellow
serratia=red (prodogesin)
pseudomaonas= bluegreen
catalase positive organism infections predisposed in which disease
chronic granulomatous disease
chronic granulomatous disease has which deficiency
NADPH oxidase
tests(2) for CGD
1 (NBT) nitro blue tetrazolium test
2 (DHR) dihydro rhodamine test
strep
alpha hemolysis=
partial/complete?
color?
partial
green
classi. of alpha hemolytic strep by?(2)
optochin sensitivity
bile solubility
@hemolyt.strep
optochin sensitive
bile soluble?
strep. pneumoneae
strp .pneumonae organism morpho
capsulated(polysacc)
diplococci
lanceolate
Carom coin
quelling’s reaction seen in?
due to ?
strp.pneumonae
capsule
mcc of lobar pneumonae
strp.pneunomiae
colony morpho of strp.pneumonae
draughtsman/ carrom coin
SHIN bacteria properties(3)
names(3)
1 polysacc capsule=vaccines
2 IgA protease
3 griffith transformation
names
1 strep pneumonae
2 haemophilous influenza
3 Neisseria meningitides
which genetic method in bacteria takes up naked DNA
transformation
which genectic method in bacteria require competence factor
transformation
strp class with complete hemolysis
beta hemolytics
classification basis for beta hemolytic strep
bacitracin sensitivity
pyr status
pyr status used to classify ?(2)
strep beta and strep gamma
color of complete hemolysis in strep
yellow
color of beta hemolysis in strep
yellow
bacitracin senitive and PYR positive?
group A
strp.pyogens
scarlet fever
erysipelas
impetigo caused by
GAS strp pyogens
bacitracin resistance
pyr negative?
grp B strp. Agalactia
hippurate hydrolysis seen in
grp B Agalactae
mcc early onset neonatal sepsis(<1 month)
meningitis
GBS Agalactae
reverse camp test for?
clostridium perfringens
Gbs
no hemolysis in which class of strep
gamma hemolytics
classification of gamma strep
growth in NaCl 6.5%
pyr status
strp showing bile solubility
gamma
pyr + grows on 6.5% NaCl
enterococcus
pyr-
Not growing on 6.5% NaCl
strp Bovis
strp Bovis aka
Strp Galactolysicus
colon ca by which strp
strp Bovis
bile esculide agar for?
enterococcus(strep)
Guttate psoriasis a/w bacteria?
beta hemolytic strep
beta hemolytic lancefield classification on basis of
carbohydrate antigen
beta hemolytic classification griffith on basis of
M protien
kerby bauver test for
disc diffusion test
antigen sensitivity
endocarditis lesions along line ofclosure in heart valve(2)
1 RHD (small)
2 marantic=non bacterial thrombotic/paraneoplastic
ring abscess in which endocarditis
infective
destruction of chorda tendonae in which endocarditid
infective
libmann sac endocarditis seen in
SLE
lesions above and under surface of chorda tendonae in
SLE /Libman ssac endocarditis
mcc acute endocarditis
staph aureus
mcc of endocarditis ivdu(iv drug users)
staph aureus
mcc of hospital acquired endocarditis
staph aureus
mcc of community acquired endocarditis by
Class?
strep viridans
Alpha sensitive
mcc of prosthetic valve infective endocarditis
CONS=staph epidermidis=biofilms
which staph produces biofils
CONS/staph epidrmidis
mcc of endocarditis associated with colon cancer
strep Bovis
g +ve bacilli Aerobes(4)
bacillus
listeria
corynaebacterium
mycobaterium
g+ve bacilli anaerobes(1)
clostridium
g+ve branching filaments
anaerobic
actinomyces
g+ve branching filament
aerobe
nocardia
g+ve branching filament acid fast
nocardia
h2so4 conc for nocardia
in AF stain
1%
h2so4 conc for leoginella in AF stain
1%
doc for nocardia infection
cotrimoxazole(tmp smx)
doc for pneumocystis jeruvecii
cotrimoxazole
cotrimoxazole contains
trimethoprime+sulfamethoxazole
doc for actinomyces
penicillin
3 disease presentation of actinomyces
1 chronic osteomyelitis of mandible
2 mycetoma foot(yellow draining sinus)
3 PID a/w IUCD
granules color in actinomyces foot
yellow
granule color in eumycetoma d/t madurella
black/brown/reddish brown
spidery colony
lumpy jaw by
actenomyces israelli
molar tooth colonies by?
actinomyces
polypeptide capsule seen in which g+ve bact
bacillus
D glutamate capsule seen in
bacillus
medussa head colonies
bacillus
mcfaeden reaction
bacillu
PLET for
b.anthrax
MYPA for
b.cereus
hemorrhagic mediastinitis seen in which g+ve bacilli
b.anthrax
inverted fir tree appearance
bacillus
jet actin motility seen in
listeria
only g+ve bact to produce endotoxin
listeria
tumbling motility
listeria
differential motility seen in
at temp?
listeria
22-25
no motility at 37 or higher
cold culture in
listeria
palcam agar for
listeria
meningitis in extreme ages by
listeria
doc for literia
ampicillin
type of rash in listeria
bull’s eye rash
drugs for meningitis
vancomycin emperical
ceftriaxone emperical
ampicillin only for extreme ages
ceftazidine
meropenem
mcc of meningitis in 2yo to 50 yo
strep pneumoniae
drugs for meningitis in neonate
3rd gen cephalosporin
ampicillin
Chinese letter arrangement
coryn.dipthyria
LSS for ?
coryn.dipthyria
K tellurite for?
coryn.dipthyria
food poisoning
early<6hrs
chinese food
B.cereus
food poisoning early<6 hrs
milk
staph. aureus
g+ve anaerobes
subterminal spores
terminal
clostridium
g+ve anaerobes
tennis racquet
clostridium tertium
g+ve anaerobe
drumstick
clostridium tetani
bull’s neck swelling
pseudomembrane
granules on albert stain
coronation.diptheri
Zn phospholipase/lecithinase
in?
alpha toxin
clostridium perfringes
naeglar test for organism?
enzyme?
breaks down?
clostridium perfringes
phospholipase/alpha toxin
egg yolk
gas gangrene caused by
clostridium perfringens
volcano erruption sign on histo
pseudomembranous enterocolitis
pseudomembranous enterocolitis cuased by
clostridium defficle
clostridium defficle toxins(2)
1 A=enterotoxin
2 B=cytotoxin
oral vancomycin given only in
pseudomembranous enterocolitis
doc for pseudomembranous enterocolitis
fidoxamycin
diagnosis pseudomembranous
PCR>ELISA
g-ve diplococcicocci
neisseria
According sign seen in
Pseudomembranous enteroxolitis
h/o wide spectrum antibiotic use (cephalosporin)
hospital admission
diarrhea
pseudomembranous enterocolitis
pseudomem.enterocol. volcano erruption sign cells?
neutrophil >lympho
colonoscopy finding in pseudomemb.enterocol
diffuse thickening of bowel/colon
maltose fermentation/ maltose acid detection in which which gram negative cooci
n.meningitidis
which type meningococci vaccine for at risk patients
type B
vaccine and polysacc capsule in which neisseria
N.meningitidis
g-ve cocci
moraxella
vilinella
diplococci=neiserria
g-ve bacilli classification on basis of
lactose fermenters
on mcConkey agar
g-ve SLOW lactose fermenting
serratia
citrobacter
g-ve FAST lactose fermenters
E.coli
klebsiella
enterobacter
contents of McConkey agar
peptone
lactose
agar
neutral red(indicator)
taurocholate
waterhouse fredrichson syndrome BY which diplococci
Neisseria meningitidis
meningitis
followed by diffuse petechial rash
shock
B/L adrenal hemorrhage
water house Frederickson syndrome
transport media for neisseria
stuart/amies
culture media for neisseria
thayer-martin
cervicitis’/urethritis
smear=intracellular diplococci
n.gonorrhea
n.cgonorrhea coexists with
chlamydia
treartment for cervicitis urethritis scrotal swelling(2)
1 cefaxime
2 azithral
gonorrhea drug
ceftriazone
chlamydia drug
azithromycin
fitz curtiz hugh syndrome by
Chlamydia
.gonorrhea PID complication
perihepatitis
violin string sign seen in
fitz curtis hugh syndrome
g-ve oxidase +ve
curved rods(all)
Shapes
campylobacter apmhitrichous
vibrio uni
helicobacter .pylori ?
skirrow’s media culture fo?
campylobacter
reiter’s syndrome caused by(2)
sheigella
campylobacter
which g-ve rod grows in 42 degree
campylobacter
g-ve curved rod that is amphitrichous
campylobact
g-ve curved rod that is monotrichous
vibrio
g-ve bacilli that is monotrichous
pseudomonas
motility by bacilus.subtulis
tumbling
motility by salmonella typhimurium
tumbling
motility by listeria and e.coli
tumbling
vibrio parahemolyiticus motility
swarming
proteus motility
swarming
clostridium motility
swarming
b.cereus motility
swarming
vibrio cholera motility
darting
TCBS culture for
vibrio cholera
string test for(2)
giardia
vibrio cholera
cary blair transtort medium for
vibrio cholera
venkutraman ramakrishnan/VR transport medium for
vibrio cholera
shellfish history in which oxidase +ve bacteria
vibrio parahemolyticus
sepsis cause by which vibrio
vibrio vulnificus
urea breath test +ve in
H.pylori
hydrogem breath test in
lactose intolerance
classification of g-ve bacilli on basis of
lactose fermenter on mcconkey agar
e.coli and klebsiella d/d by
I/M/V/C
what are IMVC test
indole
methyl red
VP
citrate
which IMVC test are positive for klebsiella
color
VP=gives red
citrate=gives blue
IMVC test +ve for E.coli
color
indole=gives red ring
methyl red =gives red color
mcc of UTI
E.coli
EMB culture media for
E.coli
CLED culture media for
E.coli
CLED/EMB for which disease
UTI
cefotixin agar culture media for
clostridium defficle
non selective culture media for UTI
E.coli
middlebrook culture med.for
TB
LJ cuture med. for
TB
chinese leter arragnement on HISTOLOGY
fibrous dysplasia
g-ve lactose NON fermenting
classified on basis of
oxidase
g-ve lactose non fermenting oxidase positive bact.(3)
pseudomonas
burkholderia
hemophilus
cetrimide agar culture media in
pseudomonas
common infection in cystic fibrosis in adults
pseudomonas
common infection in cystic fibrosis in children
staph.aureus
oxidase -ve g-ve classified on basis of
H2S production onTSI agar
TSI agar ingredients?
organisms?
triple sugar iron agar
for
1 h2s producing=salmonella
proteus
2 h2s non producing sheigella
yersinia
urease positive
oxidase negative
lactose non fermenting
g-ve bact?
proteus
diene’s phenomenon shown by
proteus
staghorn calculi by organism
proteus
bubonic plague caused by
yersinia pestis
RIF pain due to LN involvement by organism
yersinia pseudoappendisitis
pediatric diarrhea caused by pili attachment/effacement leasion in
EPEC
Sereney’ test for?
EIEC
toxin producing e.coli
ETEC
DAEC fullform
diffusely adherentE.coli
persistent diarrhea by which E.coli
EAEC(aggregating)
ecthyma gangrenosum caused in immunocompromised by
pseudomonas
ecthyma contagiosum caused by
pox -ORF virus
zoonosis disease caused by orf virus in fingers k/s
ecthyma contagiosum
most specific infection in cystic fibrosis by
burkholderia
mcc of malignant otitis externa
pseudomonas
mcc of sepsis in burns
pseudomonas
mcc of corneal ulcer in contact lens users
pseudomonas
mcc of corneal ulcer in contact lens misuse
acanthamoeba
mcc of hot tub folliculitis
pseudomonas
mcc of osteomylitis
staph aureus
mcc of osteomyelitis in nail in bone
pseudomonas
mc site involved in acute osteomyelitis due to nail
metaphysis
mcc of acute osteomyelitis in sickle cell disease
salmonella
IOC for acute osteomyelitis d/t nail
MRI (see BM edema)
reaction to detect antigen of proteus
weil felix(with rickettsia)
urine alkaline struvite syndrome by
proteus
2 species of proteus show separation of colonies in which phenomenon
diene’s phenomenon
factors needed by h.influenza to grow
5th(nad)(heat labile)
10th(hemin)
not factors
satellitism on blood agar shown by
H.influenza
blood gives which factor to H.influenza
10th
Hemin
what gives factor 5 for sattelitism to H.influenza
staph aureus(produces NAD)
diene’s staining in
mycoplasma
mollicutes/joker/no call wall in
mycoplasma
fried egg colony by which bacteria
mycoplasma
atypical walking pneumonia in
mycoplasma
PPLO culture
mycoplasma
mycoplasma shows which agglutinin
cold
IgM
g-ve spirochetes(3)
treponema
borrelia
leprospira
EMJH medium for
Leptospira
weil’s disease by
leptospira
icterohemorrhagic fever aka?
caused by?
weil’s disease/leptospirosis
leptospira
association with rat urine in paddy fields
leptospirosis
hooks present in which spirochetes
leptospira
which agglutination test in leptospira
microscopic (MAT)
dairy products food poisoning/zoonosis
brucella
SAT(standard agglutination test)for
brucella
eaton agar culture media for
mycoplasma
ashdown culture media for
burkholderia
selenite F culture media for
sheigella /salmonella
ludlams culture media for
staph aureus
mannitol salt agar culture med for
staph aureus
regan lowe culture media for
bordetella pertussis
bordet genghou culture media for
bordetella pertussis
corkscrew motility seen in
treponema
lashing motility
borrelia
borrelia recurrentis causes(2)
epidemic relapsing fever
endemic relapsing fever
epidimic relapsing fever transmitted by
louse
endemic relapsing fever transmitted by
soft tick
lyme’s disease transmitted by
hard tick
lyme’s disease caused by
borellia burkdoferri
atypical pneumonia with h/o water by
leioginella
cat scratch disease caused by
bartonella henslii
BCYE(buffer charcoal yeast) culture media for
legionella
cat scratch disease show which granuloma
stellate
erythema migrans seen in
lyme’s disease
which coxsackie cause hemorrhagic conjunctivitis
coxackie A24
castened biphasic agar for
brucella
palms and soles involving diseases(3)
sec syphilis
coxsackie A16
RMSF
great imitator
all types of rash except vescicobullous/pruritic
syphilis(sec?)
deep dermal tenderness on pressing in syphilis which sign
bushke ollendorf sign
condyloma lata by
treponema pallidum/syphilis
what type of lesion is condyloma lata
on oral mucosa
snail track lesion
condyloma accuminata caused by
HPV
primary syphilis shows
primary chncre
hard
painless
alopecia in syphilis
scarring/non scarring
moth eaten
tertiary syphilis
skin
cvs
cns
skin=gummas
cvs=aortic dissection
cns=tabes dorsalis/argyll robertson pupil(accomodates but does not react)
test to confirm syphilis
most specific
FTA ABS
epidemic typhus caused by
R.prowazekii
endemic typhys caused by
R.typhi
RMSF caused by
R.reketsii
indian tick typhus caused by
R.conori
african tick tuphus caused by
R.africae
ehrilichiosis affects
monocytes(GAME)
anaplasmosis affects
granulocytes(GAME)
rikettsial pox caused by
R.akari
scrub typhus caused by
R.tsutsugamushi
Q fever caused by
coxiella
IP for scrub typhus
1-3 weeks
7-21 days
ehrlichiosis transmit by
hard tick
anaplasmosis transmit by
hard tick
scrub typhus transmit by
mite
indian tick typhus transmit by
hard tick
babesiosis transmit by
hard tick
rekettsial pox transmit by
mite
RMSF transmit by
hard tick
african tick typhus tranmit by
hard tick
endemic typhus transmit by
flea
epidemic typhus transmit by
louse
larva of mite
chiggus
not killed by pasturization
coxiella
scrub typhus transmit by
mite
rikettsial pox transmit by
mite
cremean congo hemorrhagic fever transmit by
hard tick
kyanasaur forest disease transmit by
hard tick
orrentia transmit by
mite
red colored
transovarian transmission by
mite
D.lataum transmission by
cyclops
mosquito
mosquito sitting at angle
anopheles’
mosquito parallel to body
aedes
mosquito with hunchback
culex
mosquito with pistia plant
mansonia
mosquito in clean water
aenopheles
mosquito in artficial water
aedes
mosquito in dirty water
culex
mosquito with shortest flight
aedes(100m)
mosquito with largest flight
culex(10km)
mosquito with stripes on body
aedes
mosquito spotted wings
anopheles
mosquito causing malaria
anopheles female
mosquito causing dengue
aedes
mosquito causing chikungunya
aedes
mosquito causing yellow fever
aedes
mosquito causing west nile fever
culex
mosquitocausing zika virus fever
aedes
mosquito causing rift valley fever
aedes
mosquito causing JE
cules
mosquito causing filariasis by w.bankrofti
culex
mosquito causing filariasis by brugia malayi
mansonia
breateau index seen in
dengue
virus a/w pig
fruit bat
palm tree
nipah
virus a/w bat
deer
ebola
dead end/accidental host in JE
humans
amplifiers in JE
pig
amplifier that is vaccinated in JE
pig
reservoir in JE
water fowl
hairy sand fly transmit
kala azar
Rk39 text +ve in
kala azar
kinetoplast
geimsa stain in?
kala azar
amastigotes seen in
kala azar
LD bodies seen in
kala azar
fever+hsm+bihar/jharkhand
kala azar
monternegro test in
kala azar
JSB stain for peripheral smear in
malaria
smear for species identificatio
thin
smear for sensitivity/+/_
thick
1 microscope in _ population in malaria
25k
most imp measure of malaria control
annual parasite index
best indicator for operational efficacy
annual blood examination rate
best during outbreak
slide positivity rate