derma Flashcards
1
Q
fully keratinized non nuclear cells in which layer on skin
A
stratum corneum
2
Q
stratum lucidum is present in
A
palms and soles
3
Q
keratinocytes are present in which layer of skin
A
st. granulosum
4
Q
fillagrin is present in which cells
A
keratinocytes
5
Q
atopic dermatitis is caused due to defect in what?
in what layer?
A
keratinocytes
st granulosum
6
Q
icthyosis is due to deficiency of what?
A
filaagrin
7
Q
icthyosis is in which layer
A
st granulosum
8
Q
fish net appearance on skin seen in
A
ichthyosis
9
Q
lamelar odland bodies are in layer?
A
st granulosum
10
Q
asteatotic eczema due to deficiency of
A
lipid barrier
lamellar odland bodies
11
Q
langerhans cells present in which layer of skin
A
st spinosum
12
Q
cd 207 cd 1a+
A
langrin
13
Q
thickest layer of skin
A
st spinosum
14
Q
desmoglien 1 and 3 present in which layer
A
st spinousum
15
Q
acanthocytes present in which layer
A
st spinosum
16
Q
bierbicks granuales secret what
A
langrin
17
Q
bierbicks granuales present in which cells
A
langrerhan cells
18
Q
which layer is single celled in skin
A
st basale
columnar
19
Q
merkle cells present in which layer
A
st basale
20
Q
melanocytes are present in which layer
A
st basale
21
Q
keratinocytes are present in which layer
A
all layers
22
Q
merkle cells are derived from
A
ectoderm
23
Q
melanocytes are derived from
A
ncc
24
Q
which cells of skin are APC
A
langerhan cells
25
markers of melanin
HMB 45
melan A
S 100
26
marker of merkle cells
ck20+
ck 7-
27
keratinocytes derived from
ectoderm
28
90% of skin cells are
keratinocytes
29
hallmark of keratinocytes
keratin intermediate filament
30
orthokeratosis?
increased number of keratinocytes in st corneum
31
hyperkeratosis?
increased number of keratinocytes and nucleus in st corneum
32
parakeratosis?
nucleus in st corneum
33
epidermal melanin unit
1:36
1 melanocytes-- 36 keratinocytes
34
epidermal transit time
28 days
35
epidermal turnover time
56 days
36
agranulocytosis present in which disease
psoriasis
37
munro's microabscess are present in which disease?
in which layer?
psoriasis
st corneum
38
8 lesions seen in psoriasis
agranulocytosis
munros microabscess
hyperkeratosis
camel foot club shaped rete ridges
suprapapillary epidermal plate thinning
spongiform pustules of koyog
dilated vessles with surrounding inflammation
parakeratosis
39
psoriasis lesion are commonly seen on extensors or flexors
extensors
40
spongiform pustules of koyog are present in which disease ?
in which layer
psoriasis
st spongiosum
41
irregular coarse and deep pitting in nails in
psoriasis
42
7 lesions in lichen planus
hypergranulosis/wickhams stria
orthokeratosis
max joseph space
civatte bodies/councilman bodies/apoptotic neutrophil
lichenoid plane of inflammation
increased langerhan cells
spongiosis
43
lichen planus a/w which infection
Hep c
44
wickhams stria seen in
lichen planus
45
councilman bodies seen in
lichen planus
46
civatte bodies seen in
lichen planus
47
spongiosis is seen in which disease anomg l/p
lichen planus
48
erythema nodosum seen in
sulfa drugs
sarcoidosis
tb
ibd
bechets
49
which erythema is a type panniculitis
erythema nodosum
50
heerfordt syndrome
sarcoidosis with b/l facial nerve palsy
51
lofgrens syndrome
sarcoidosis with b/l hilar ln enlargement and erythema nodosum
52
miculikz syndrome
sarcoidosis with uveoparotid fever
53
hla b 51
hla 5 a/w
bechets disease
54
erythema marginatum seen in
rheumatic fever along with polyarthralgia chorea murmur
55
evanescent transient lesion a/w fever
erythema marginatum
56
erythema multiforme a/w with infection
hsv
mycoplasm
57
erythema multiforme with which drugs
nsaids cloroquine
58
chloroquine causes what in eye?
in skin?
bulls eye maculopathy /fundus
erythema multiforme
59
earliest manifestation of lyme's disease
erythema migrans
60
lyme's disease is caused by
borellia burkdoferi
61
lymes's disease is spread by
hard tick
62
polyarthralgia with chorea
acute rheumatic fever with erythema marginatum
63
nsaids cause which erythema
erythema multiforme
64
scales that change appearance on wetting
psoriasis
65
papulosquamous disease with hallmark silvery scales
psoriasis
66
oil drop lesion on nails hallmark of
psoriasis
67
subungual hyperkeratosis seen in
psoriasis
68
DIP most commonly involved in which disease
psoriasis
69
grattage test positive in
psoriasis
70
membrane removed in grattage test
Berkley's membrane
71
petechae after scrapping membrane in psoriasis which sign
aushpitz membrane
72
h/o RTI then sudden onset rain drop lesions
guttate psoriasis
73
guttate psoriasis after RTI by
beta hemolytic strep
74
Drug of choice for psoriasis
Methotrexate
75
Drug of choice for psoriasis with arthritis
aprepitant
76
Worn off
ring seen in
After
In psoriasis after phototherapy or topical therapy
77
Silvery scales seen in
Psoriasis
78
Management of guttate psoriasis
Macrolides
UVB rays
Topical steroids
79
Psoriasis after sudden withdrawal of steroids
Pustular psoriasis
80
Pustular psoriasis in pregnancy known as
Impetigo Herpetiformis
81
Drug of choice for pustular psoriasis
Acetretin
82
Drug of choice for pustular psoriasis in pregnancy
Steroids
83
Wash out period for acetretin
3years
84
Wash out period For isotretinoin
1to 3months
85
Second line for Pustular psoriasis
Coal Tar
Dithranol
86
Auspitz sign absent in Which psoriasis
Pustular and guttate
87
rupoid psoriasis
Inverse psoriasis scales on flexor axilla umbilicus Gluteal cleft Sub mammary folds
88
Kobners phenomena seen in
L P V
89
Reverse Koebner's Phenomena seen in
PV
Psoriasis
Vitiligo
90
Reverse koebners In Vitiligo
Repigmentation
Distant to graft
91
Pseudo Koebner's phenomena seen in
Viral warts
molescum Contiguousum
92
Purple plain topped pruritic Papule
lichen planus
93
Wickham's Stria seen in
Lichen planus
94
Management of lichen planus
Topical steroids
95
Type of pterigium/ pup tenting in lichen planus
Dorsal
96
Ventral pterigium Seen in
Systemics sclerosis
Raynaud's phenomena
infection
97
Lacey reticular membrane seen in mouth associated with hepatitis c
lichen planus
98
Claw clutching a ball appearance
lichen nitidus
99
Cells seen in lichen nitidus Lesion
Neutrophils
100
White membranes on oral mucosa associated with E B V
oral hairy Leukoplakia
101
Oral membrane White that can be removed
Candida
102
HHV 6 and 7 Cause
Pityriasis rosea
103
Christmas tree pattern seen in
pityriasis rosea
Myotonic dystrophy cataract neurogenic bladder in Radio
104
Which comes first in pityriasis rosea Christmas tree appearance or colorette scale patch
Colorette Scales Or cigarette paper Scales
105
Adherent rim around detachable inner lesion seen in
Herald Patch / colorette scale/ cigarette Paper scales
106
pityriasis rosea Can be caused by
HHV 6 and 7
herpes
H1N1
covid
Bacteria
107
Malasazia Globosa malasazia furfur cause
pityriasis versicolor
108
Hypo pigmentation and hyperpigmentation Scene in which tinea
Tinea versicolor/pityriasis versicolor
109
Hypo pigmentation in Tinea Versicolor due to
azelic Acid
110
Tinea versicolor on Woods lamp gives what colour
Faint yellow
111
Spaghetti and meatball Appearance
seen in
on
Pityriasis versicolor
KoH
112
Olive oil added on S D A for
Malasazia
113
Besnier's sign seen in
pityriasis versicolor
114
coup De ongle
Scratch on lesion causes loosening of scales
115
