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AM > derma > Flashcards

derma Flashcards

1
Q

fully keratinized non nuclear cells in which layer on skin

A

stratum corneum

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2
Q

stratum lucidum is present in

A

palms and soles

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3
Q

keratinocytes are present in which layer of skin

A

st. granulosum

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4
Q

fillagrin is present in which cells

A

keratinocytes

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5
Q

atopic dermatitis is caused due to defect in what?
in what layer?

A

keratinocytes
st granulosum

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6
Q

icthyosis is due to deficiency of what?

A

filaagrin

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7
Q

icthyosis is in which layer

A

st granulosum

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8
Q

fish net appearance on skin seen in

A

ichthyosis

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9
Q

lamelar odland bodies are in layer?

A

st granulosum

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10
Q

asteatotic eczema due to deficiency of

A

lipid barrier
lamellar odland bodies

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11
Q

langerhans cells present in which layer of skin

A

st spinosum

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12
Q

cd 207 cd 1a+

A

langrin

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13
Q

thickest layer of skin

A

st spinosum

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14
Q

desmoglien 1 and 3 present in which layer

A

st spinousum

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15
Q

acanthocytes present in which layer

A

st spinosum

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16
Q

bierbicks granuales secret what

A

langrin

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17
Q

bierbicks granuales present in which cells

A

langrerhan cells

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18
Q

which layer is single celled in skin

A

st basale
columnar

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19
Q

merkle cells present in which layer

A

st basale

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20
Q

melanocytes are present in which layer

A

st basale

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21
Q

keratinocytes are present in which layer

A

all layers

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22
Q

merkle cells are derived from

A

ectoderm

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23
Q

melanocytes are derived from

A

ncc

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24
Q

which cells of skin are APC

A

langerhan cells

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25
Q

markers of melanin

A

HMB 45
melan A
S 100

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26
Q

marker of merkle cells

A

ck20+
ck 7-

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27
Q

keratinocytes derived from

A

ectoderm

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28
Q

90% of skin cells are

A

keratinocytes

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29
Q

hallmark of keratinocytes

A

keratin intermediate filament

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30
Q

orthokeratosis?

A

increased number of keratinocytes in st corneum

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31
Q

hyperkeratosis?

A

increased number of keratinocytes and nucleus in st corneum

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32
Q

parakeratosis?

A

nucleus in st corneum

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33
Q

epidermal melanin unit

A

1:36
1 melanocytes– 36 keratinocytes

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34
Q

epidermal transit time

A

28 days

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35
Q

epidermal turnover time

A

56 days

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36
Q

agranulocytosis present in which disease

A

psoriasis

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37
Q

munro’s microabscess are present in which disease?
in which layer?

A

psoriasis
st corneum

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38
Q

8 lesions seen in psoriasis

A

agranulocytosis
munros microabscess
hyperkeratosis
camel foot club shaped rete ridges
suprapapillary epidermal plate thinning
spongiform pustules of koyog
dilated vessles with surrounding inflammation
parakeratosis

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39
Q

psoriasis lesion are commonly seen on extensors or flexors

A

extensors

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40
Q

spongiform pustules of koyog are present in which disease ?
in which layer

A

psoriasis
st spongiosum

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41
Q

irregular coarse and deep pitting in nails in

A

psoriasis

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42
Q

7 lesions in lichen planus

A

hypergranulosis/wickhams stria
orthokeratosis
max joseph space
civatte bodies/councilman bodies/apoptotic neutrophil
lichenoid plane of inflammation
increased langerhan cells
spongiosis

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43
Q

lichen planus a/w which infection

A

Hep c

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44
Q

wickhams stria seen in

A

lichen planus

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45
Q

councilman bodies seen in

A

lichen planus

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46
Q

civatte bodies seen in

A

lichen planus

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47
Q

spongiosis is seen in which disease anomg l/p

A

lichen planus

48
Q

erythema nodosum seen in

A

sulfa drugs
sarcoidosis
tb
ibd
bechets

49
Q

which erythema is a type panniculitis

A

erythema nodosum

50
Q

heerfordt syndrome

A

sarcoidosis with b/l facial nerve palsy

51
Q

lofgrens syndrome

A

sarcoidosis with b/l hilar ln enlargement and erythema nodosum

52
Q

miculikz syndrome

A

sarcoidosis with uveoparotid fever

53
Q

hla b 51
hla 5 a/w

A

bechets disease

54
Q

erythema marginatum seen in

A

rheumatic fever along with polyarthralgia chorea murmur

55
Q

evanescent transient lesion a/w fever

A

erythema marginatum

56
Q

erythema multiforme a/w with infection

A

hsv
mycoplasm

57
Q

erythema multiforme with which drugs

A

nsaids cloroquine

58
Q

chloroquine causes what in eye?
in skin?

A

bulls eye maculopathy /fundus
erythema multiforme

59
Q

earliest manifestation of lyme’s disease

A

erythema migrans

60
Q

lyme’s disease is caused by

A

borellia burkdoferi

61
Q

lymes’s disease is spread by

A

hard tick

62
Q

polyarthralgia with chorea

A

acute rheumatic fever with erythema marginatum

63
Q

nsaids cause which erythema

A

erythema multiforme

64
Q

scales that change appearance on wetting

A

psoriasis

65
Q

papulosquamous disease with hallmark silvery scales

A

psoriasis

66
Q

oil drop lesion on nails hallmark of

A

psoriasis

67
Q

subungual hyperkeratosis seen in

A

psoriasis

68
Q

DIP most commonly involved in which disease

A

psoriasis

69
Q

grattage test positive in

A

psoriasis

70
Q

membrane removed in grattage test

A

Berkley’s membrane

71
Q

petechae after scrapping membrane in psoriasis which sign

A

aushpitz membrane

72
Q

h/o RTI then sudden onset rain drop lesions

A

guttate psoriasis

73
Q

guttate psoriasis after RTI by

A

beta hemolytic strep

74
Q

Drug of choice for psoriasis

A

Methotrexate

75
Q

Drug of choice for psoriasis with arthritis

A

aprepitant

76
Q

Worn off
ring seen in
After

A

In psoriasis after phototherapy or topical therapy

77
Q

Silvery scales seen in

A

Psoriasis

78
Q

Management of guttate psoriasis

A

Macrolides
UVB rays
Topical steroids

79
Q

Psoriasis after sudden withdrawal of steroids

A

Pustular psoriasis

80
Q

Pustular psoriasis in pregnancy known as

A

Impetigo Herpetiformis

81
Q

Drug of choice for pustular psoriasis

A

Acetretin

82
Q

Drug of choice for pustular psoriasis in pregnancy

A

Steroids

83
Q

Wash out period for acetretin

A

3years

84
Q

Wash out period For isotretinoin

A

1to 3months

85
Q

Second line for Pustular psoriasis

A

Coal Tar
Dithranol

86
Q

Auspitz sign absent in Which psoriasis

A

Pustular and guttate

87
Q

rupoid psoriasis

A

Inverse psoriasis scales on flexor axilla umbilicus Gluteal cleft Sub mammary folds

88
Q

Kobners phenomena seen in

A

L P V

89
Q

Reverse Koebner’s Phenomena seen in

A

PV
Psoriasis
Vitiligo

90
Q

Reverse koebners In Vitiligo

A

Repigmentation
Distant to graft

91
Q

Pseudo Koebner’s phenomena seen in

A

Viral warts
molescum Contiguousum

92
Q

Purple plain topped pruritic Papule

A

lichen planus

93
Q

Wickham’s Stria seen in

A

Lichen planus

94
Q

Management of lichen planus

A

Topical steroids

95
Q

Type of pterigium/ pup tenting in lichen planus

A

Dorsal

96
Q

Ventral pterigium Seen in

A

Systemics sclerosis
Raynaud’s phenomena
infection

97
Q

Lacey reticular membrane seen in mouth associated with hepatitis c

A

lichen planus

98
Q

Claw clutching a ball appearance

A

lichen nitidus

99
Q

Cells seen in lichen nitidus Lesion

A

Neutrophils

100
Q

White membranes on oral mucosa associated with E B V

A

oral hairy Leukoplakia

101
Q

Oral membrane White that can be removed

A

Candida

102
Q

HHV 6 and 7 Cause

A

Pityriasis rosea

103
Q

Christmas tree pattern seen in

A

pityriasis rosea
Myotonic dystrophy cataract neurogenic bladder in Radio

104
Q

Which comes first in pityriasis rosea Christmas tree appearance or colorette scale patch

A

Colorette Scales Or cigarette paper Scales

105
Q

Adherent rim around detachable inner lesion seen in

A

Herald Patch / colorette scale/ cigarette Paper scales

106
Q

pityriasis rosea Can be caused by

A

HHV 6 and 7
herpes
H1N1
covid
Bacteria

107
Q

Malasazia Globosa malasazia furfur cause

A

pityriasis versicolor

108
Q

Hypo pigmentation and hyperpigmentation Scene in which tinea

A

Tinea versicolor/pityriasis versicolor

109
Q

Hypo pigmentation in Tinea Versicolor due to

A

azelic Acid

110
Q

Tinea versicolor on Woods lamp gives what colour

A

Faint yellow

111
Q

Spaghetti and meatball Appearance
seen in
on

A

Pityriasis versicolor
KoH

112
Q

Olive oil added on S D A for

A

Malasazia

113
Q

Besnier’s sign seen in

A

pityriasis versicolor

114
Q

coup De ongle

A

Scratch on lesion causes loosening of scales

115
Q
A

AM (12 decks)

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