Metronidazole - miscellaneous Flashcards

1
Q

MOA

A

bactericidal

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2
Q

Use indications

A

excellent anaerobic and antiprotozoal efficacy

kills CLOSTRIDUM DIFFICILE - an important pathogen responsible for many post-oral antibiotic GIT toxins

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3
Q

Spp application

A

Used in horses (TMS can cause over growth of C.difficle)

occasionally used in small animals

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4
Q

Side effects/contraindications

A

Used predominantly for anaerobic coverage e.g. tetanus

complicated IV dosage rates

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5
Q

PK quirks

A

synergy with beta-lactems

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