Metronidazole - miscellaneous Flashcards
1
Q
MOA
A
bactericidal
2
Q
Use indications
A
excellent anaerobic and antiprotozoal efficacy
kills CLOSTRIDUM DIFFICILE - an important pathogen responsible for many post-oral antibiotic GIT toxins
3
Q
Spp application
A
Used in horses (TMS can cause over growth of C.difficle)
occasionally used in small animals
4
Q
Side effects/contraindications
A
Used predominantly for anaerobic coverage e.g. tetanus
complicated IV dosage rates
5
Q
PK quirks
A
synergy with beta-lactems