Lincosamides - antimicrobial

Question 1

MOA

Answer 1

inhibits protein synthesis

concentrates in phagocytes so is taken to infected tissues

Question 2

Use indications

Answer 2

• similar spectrum to macrolide but higher anaerobic infection
  coverage e.g. Clostridum spp.
• important coverage against toxoplasma
• used to treat gram +ve when there is resistance to penicillin i.e clostridium spp
  -well suited to abscess, wounds, none infections and periodontal disease

Question 3

Spp application

Answer 3

Dogs - for treatment of dental infections, wounds abscesses

Question 4

Representative drugs

Answer 4

Clindamycin