Anti-ulcers - drugs that ameliorate GI ulcers Flashcards

1
Q

Omeprazole

MOA?

A

Proton pump inhibitor

most effective and expensive

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2
Q

Ranitidine
Sucralfate (crush enormous tablets and make into a liquid)
MOA?

A

H2 antagonist

Sucralfate is not that great because it required an ulcer to work

Horse = omeprazole and ranitidine
SA = omeprazole, sucralfate, ranitidine
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3
Q

Cause of stomach ulcers?

A

overzealous NSAIDs, corticosteriods, stress etc. Hydrogen ions (acid) secreted into the stomach lumen by the parietal cell through H+ K+ ATPase

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