Anti-ulcers - drugs that ameliorate GI ulcers Flashcards
1
Q
Omeprazole
MOA?
A
Proton pump inhibitor
most effective and expensive
2
Q
Ranitidine
Sucralfate (crush enormous tablets and make into a liquid)
MOA?
A
H2 antagonist
Sucralfate is not that great because it required an ulcer to work
Horse = omeprazole and ranitidine SA = omeprazole, sucralfate, ranitidine
3
Q
Cause of stomach ulcers?
A
overzealous NSAIDs, corticosteriods, stress etc. Hydrogen ions (acid) secreted into the stomach lumen by the parietal cell through H+ K+ ATPase