metformin

Question 1

Generic name of metfomrkn

Answer 1

Glucophage

Question 2

What class of medications is metformin?

Answer 2

Biguanide

Question 3

Describe action of metformin

Answer 3

decreased hepatic gluconeogenesis
Increase peripheral insulin sensitivity, decrease intestinal absorption of glucose,
does not cause weight gain

Question 4

what is the change in a1c of metformin

Answer 4

1 to 2%

Question 5

what are the contraindications of metformin

Answer 5

creatinine greater than 1.5 in men and 1.4 in women, hepatic dysfunction, acidosis, hypoxia, increased alcohol intake, taking drugs for congestive heart failure

Question 6

what are the side effects of taking metformin

Answer 6

nausea and diarrhea, must take with food or milk, ok to take with pregnancy

Question 7

why should you stop metformin

Answer 7

IV contrast, acute hypoxia, need to have normal renal function before starting.
acute myocardial infarction, acute exacerbation of congestive heart failure, major surgical procedures, metformin is excreted by kidneys which is why patients with renal dysfunction should not be on it , should not take with hepatic dysfunction because lactate metabolism is carried out by the liver andbecause this can predispose them to lactic acidosis

Question 8

Can someone take metformin if they’re not making enough insulin

Answer 8

metformin has proven to be an effective antihyperglycemic agent but requires endogenous insulin production for its effectiveness

Question 9

metformin doses

Answer 9

500 2550 milligrams daily, max effective 2000 milligram daily, initiated at low dose, take those is just before meals, can be taken in children 10 years of age or older starting at 250 milligrams twice daily

Question 10

describe effects of metformin on pregnancy

Answer 10

FDA approved for pregnancy, questionable whether metformin is excreted through human milk, nursing women should discontinue metformin or discontinue nursing to avoid hypoglycemia and breastfeeding infants

Question 11

positive side effects of taking metformin

Answer 11

2 - 5 kilogram weight loss, triglycerides reduced by 16%, LDL cholesterol reduced by 8%, total cholesterol reduced by 5%, HDL increased by 2%

Question 12

instructions for patience about metformin

Answer 12

take with food to reduce GI side effects, combination therapies can cause hypoglycemia promise women of reproductive age can get pregnant because metformin can restore ovulation and women due to insulin resistance previously, 30% of users have GI side effects not go away in 7 to 14 days, metallic taste in mouth will go away with time