Metabolism phases + Enzymes Flashcards

1
Q

Phase I Metabolismus

A

Funktionalisierung von Substanzen

Oxidation (CYP)
Reduktion (ADH, ALDH)
Epoxidreduktion (FAD)

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2
Q

Phase II Metabolismus

A

Konjugationsreaktionen (hydrophiler machen)

Glukoronosyltransferasen (UGT)
Glutathion-S-Transferasen (GST)
N-Acetyltransferasen (NAT)
Sulfotransferasen (SULT)

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3
Q

Phase III Metabolismus

A

Aufnahmetransporter → org. Anion & Kation Transporter

Eliminationstransporter → ATP-abhängige Transporter

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