Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PMU Biochemistry > Metabolism of Phospho- and Sphingolipids, Inositol Phosphates > Flashcards

Metabolism of Phospho- and Sphingolipids, Inositol Phosphates Flashcards

1
Q

What is the main group of lipids

A

TAG, GPL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Where are TAGs

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are Glycerphospholipids - structure, properties, where are they present

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are Sphingolipids - structure, properties

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the membrane lipids

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Give examples of a glycerophospholipid with specialised function

A

Dipalmitoylphosphatidyl Choline
Phosphatidylinositols
PAF - Platelet-activating factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the structure of Dipalmitoylphosphatidyl Choline (Dipalmitoyl Lecithin)

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How is Diplamitoylphosphatidyl Choline synthesised

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the function of Diplamitoylphosphatidyl Choline

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the different Phosphatidylinositols

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is PIP2

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is PIP3

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the function of PAF (Platelet-activating factor)

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the structure of PAF (Platelet-activating factor)

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the 3 examples of Glycosphingolipids

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What do the carbohydrate residue of Glycosphingolipids participate in

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Describe Cerebrosides

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Describe Gaucher Disease (in relation to cerebrosides)

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Where are galactocerebrosides predominantly found

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Where are glucocerebrosides predominantly found

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What are the 3 Sphingolipids with specialised function

A

Globosides
Sulfatides
Gangliosides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What are Globosides

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are Sulfatides

A

.

24
Q

What are Gangliosides - description, where are they present and what is their role

A

e.g GM2

25
Q

What are the sphingolipids involved in cell signalling

A

.

26
Q

What is the role of Sphingosine-1-Phosphate SP1

A

.

27
Q

What is the role of Ceramide-1-Phosphate C1P

A

.

28
Q

What are the roles of sphingosine and ceramide in cell signalling

A

.

29
Q

Where are ceramide derived from

A

.

30
Q

Describe the relationship of sphingolipids with Blood Type Antigens

A

.

31
Q

How are Glycophospholipids formed

A

.

32
Q

What are the substrates for Glycerphospholipids synthesis

A

.

33
Q

The substrates for Glycerphospholipids synthesis include FAs, what needs to happen to the FAs for the process to further

A

.

34
Q

How does the body obtain Glycerol-3-Phosphate

A

HINT: Glycerol Kinase, Glycerol-3-P DH

35
Q

How does the degradation of glycerophospholipids occur and why is it possible

A

.

36
Q

What are the different Phospholipases

A

.

37
Q

All Sphingolipids are synthesised on the base of what?

A

.

38
Q
  1. What is the first step of Sphingolipid synthesis
A

HINT: 18-C formed

39
Q
  1. What is the second step of Sphingolipid synthesis
A

HINT: amide linkage formed

40
Q
  1. What is the third step of Sphingolipid synthesis
A

HINT: double bond added

41
Q
  1. What is the fourth step of Sphingolipid synthesis
A

HINT: attachment of head group

42
Q

In what organelle does sphingolipids synthesise

A

.

43
Q

What degrades gangliosides

A

.

44
Q

What does pulmonary surfactant contain

A

.

45
Q

What is the function of pulmonary surfactant

A

.

46
Q

The deficiency of pulmonary surfactant in premature infants is known as - what is the treament

A

.

47
Q

What are the 2 diseases that involve phospholipids PL and Sphingolipids SpL

A

.

48
Q

What occurs in Multiple Sclerosis, in terms of PL and SpL

A

.

49
Q

What is Sphingolipidosis

A

.

50
Q

What enzyme is deficient in General Gangliosidosis

A

.

51
Q

What enzyme is deficient in Tay-Sachs disease

A

.

52
Q

What is Tay-Sachs disease and what are the symptoms

A

.

53
Q

What enzyme is deficient in Gaucher’s disease

A

.

54
Q

What is Gaucher’s disease and what are the symptoms

A

.

55
Q

What enzyme is deficient in Niemann-Pick disease

A

.

56
Q

What is Niemann-Pick disease and what are the symptoms

A

.

57
Q

What enzyme is deficient in Fabry’s disease

A

.

PMU Biochemistry (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions