Metabolism 64 Flashcards
List the sources of free amino acids in the body
- Ingested proteins
- Biosynthesis
- Protein breakdown
How much protein must be present in the diet to maintain body protein?
55g
Positive Nitrogen balance in what situations?
- Pregnant women
- Growth in children
- Body building
Negative Nitrogen balance in what situations?
- trauma
- burn injury
- infection
- cancer
- sepsis
- surgery
The reasons for nitrogen degradation
- form urea for excretion of nitrogen
- degradation of carbon skeletons is used for energy production or storage for glycogen or fat
Describe the transamination in terms of substrates, products, and cofactors
- amino acid & alpha ketoglutarate
- compound and glutamate
- pyridoxal phsophate
How is glutamate is converted to aspartate and ammonia?
- aspartate transaminase
- glutamate dehydrogase
Primary regulated enzyme in the urea cycle?
N-acetylglutamate
Enzyme that produces urea from arginine
Arginase
Which two amino acids are major transporters to the liver?
Glutamine & Alanine