Metabolism 64 Flashcards

1
Q

List the sources of free amino acids in the body

A
  • Ingested proteins
  • Biosynthesis
  • Protein breakdown
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2
Q

How much protein must be present in the diet to maintain body protein?

A

55g

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3
Q

Positive Nitrogen balance in what situations?

A
  • Pregnant women
  • Growth in children
  • Body building
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4
Q

Negative Nitrogen balance in what situations?

A
  • trauma
  • burn injury
  • infection
  • cancer
  • sepsis
  • surgery
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5
Q

The reasons for nitrogen degradation

A
  • form urea for excretion of nitrogen

- degradation of carbon skeletons is used for energy production or storage for glycogen or fat

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6
Q

Describe the transamination in terms of substrates, products, and cofactors

A
  • amino acid & alpha ketoglutarate
  • compound and glutamate
  • pyridoxal phsophate
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7
Q

How is glutamate is converted to aspartate and ammonia?

A
  • aspartate transaminase

- glutamate dehydrogase

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8
Q

Primary regulated enzyme in the urea cycle?

A

N-acetylglutamate

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9
Q

Enzyme that produces urea from arginine

A

Arginase

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10
Q

Which two amino acids are major transporters to the liver?

A

Glutamine & Alanine

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