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Physiology section 3 > Metabolism 63 > Flashcards

Metabolism 63 Flashcards

1
Q

What does Apo-CII do?

A

Activates lipoprotein lipase

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2
Q

What does Apo-AI do?

A

activates lecithin; cholesterol acyltransferase (LCAT)

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3
Q

Apo E is a ligand for what type of receptor?

A

Remnant Receptor

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4
Q

Apo B-100 is a ligand for what type of receptor?

A

LDL

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5
Q

Apo A-I is a ligand for what type of receptor?

A

HDL

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6
Q

B-48 is a structural protein of which lipoprotein?

A

Chylomicrons

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7
Q

B-100 is a structural protein of which lipoproteins?

A

LDL & VLDL

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8
Q

A-1 is a structual protein of which lipoproteins?

A

HDL

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9
Q

Which lipoprotein has the highest fat/protein ratio?

A

Chylomicrons

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10
Q

Which lipoprotein has the lowest fat/protein ratio?

A

HDL

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11
Q

Where are Chylomicrons formed?

A

Intestines

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12
Q

What is the function of Chylomicrons?

A

To transport dietary TAG to adipose and other tissues

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13
Q

What is the function of the Chylomicron remnant?

A

To transport remaining dietary TAG to liver

-exchanges TAG for cholesterol ester (CE) from HDL; delivers cholesterol ester (CE) to liver

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14
Q

Where is VLDL formed?

A

Liver

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15
Q

What is the function of VLDL?

A

Transports endogenously synthesized TAG to adipose tissue, heart, and skeletal muscle

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16
Q

What is the function of IDL?

A
  • Delivers remaining TAG and cholesterol ester to liver

- exchanges TAG for cholesterol ester (CE) from HDL; delivers cholesterol ester (CE) to liver

17
Q

What is the function of LDL?

A

Delivers cholesterol to liver and other cells

18
Q

Where is HDL formed?

A

Mostly liver, some in intestines

19
Q

What is the function of HDL?

A
  • Accepts cholesterol from peripheral cells, esterifies it, and transports the CE to the liver
  • Exchanges CE for TAG in LDL, VLDL, and Chylomicron remnants
  • Atheroprotective by inhibiting LDL oxidation
  • reservoir for Apo proteins

Physiology section 3 (18 decks)

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