Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Physiology section 3 > GI Lecture 48 & 49 > Flashcards

GI Lecture 48 & 49 Flashcards

1
Q

Where is intrinsic factor made? What does it for?

A

In the stomach. essential for the absorption of vitamin B12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are forms of neural regulation of stomach?

A

Instrinsic

Extrinsic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are endocrine effectors that regulate gastric secretion?

A
  • Gastrin (stomach and duodenum)

- Somatostatin (stomach, duodenum, and pancreas)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the luminal secretions of the funds and body?

A
  • H+
  • Intrinsic Factor
  • Mucus
  • HCO3-
  • Pepsinogen
  • Lipase
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What do all parts of the stomach secrete luminally?

A
  • HCO3-

- Mucus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Defense mechanisms of the GI System

A
  • Salivary lysozyme
  • gastric HCl secretion
  • liver detox
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Six cell types in fundus and antrum

A
  • Parietal cells
  • Mucous neck cells
  • Peptic/Chief cells
  • Enterochromaffin-like (ECL) cells
  • D cells
  • G cells
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Parietal cells secrete:

A
  • HCL

- Intrinsic Factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Mucous necks cells secrete:

A

Mucus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Peptic/Chief cells secrete:

A

Pepsinogens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Entrochromaffin-like (ECL) cells secrete:

A

Histamine

-most powerful stimulator of HCl secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

D cells secrete:

A

Somatostatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

G cells secrete:

A

Gastrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Parietal cell secretion mechanism:

A
  • Once activated, tubulovesicular membranes (containing H & Cl transport proteins) fuse with the already present intracellular canaliculi
  • Ultimately, increases the number of H-K antiporters on secretory canaliculi
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the alkaline tide? Where does it occur? How is it rectified?

A
  • pH increase in venous blood near stomach due to pumping out of HCO3- during active H+ secretion
  • rectified by pancreatic HCO3- secretion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What pump do H+ inhibitors target?

A

K+ - H+ pump on lumen side of parietal cell

17
Q

How does Cl- get secreted?

A

Follows H+ that was secreted by diffusing through Cl- channels

18
Q

Why must there be a constant secretion of mucin in the stomach?

A

-Pepsin is only functional as a tetramer and pepsin constantly degrades it

19
Q

How does Acetylcholine simulate gastric secretion?

A

binds to muscarinic receptors on the parietal cells and directly on the ECL cells
-secondary messengers are IP3/Ca++

20
Q

How does Histamine stimulate gastric secretion?

A

Histamine secreted from ECL cells bind to H2 receptors (parietal cells)
-secondary messenger is cAMP

21
Q

How does Gastrin stimulate gastric secretion?

A

secreted by G cells and binds to CCKB receptors on parietal cells
-secondary messengers are IP3/Ca++

Physiology section 3 (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions