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Physiology section 3 > Metabolism 55 & 56 > Flashcards

Metabolism 55 & 56 Flashcards

1
Q

Glucagon/Epinephrine promote

A
  • Gluconeogenesis

- Glycogenolysis

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2
Q

GLUT2 transporter

A

-insulin independent

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3
Q

GLUT4 transporter

A

-insulin dependent

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4
Q

Irreversible glycolytic enzymes (3)

A
  • Hexokinase/Glucokinase
  • Phosphofructokinase - 1 (PFK - 1)
  • Pyruvate Kinase
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5
Q

Activators of PFK - 1

A
  • AMP

- Fructose 2,6 biphosphate

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6
Q

Inhibitors of PFK - 1

A
  • ATP

- Citrate

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7
Q

How is PFK - 2 regulated?

A
  • Glucagon/Epinephrine

- inactivates through phosphorylation by PKA

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8
Q

Effects of epinephrine on glycolysis

A
  • inhibits glycolysis in liver

- activates glycolysis in heart and muscle

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9
Q

How is Pyruvate kinase regulated?

A
  • Glucagon/Epinephrine cause inactivation thorugh phosphorylation by PKA
  • Insulin re-activates with phosphoprotein phosphatase
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Physiology section 3 (18 decks)

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