GI Lecture 44 & 45 Flashcards
Major physiological processes of GI Tract (4)
- Motility
- Secretion
- Digestion
- Absorption
Celiac artery profuses?
- liver
- spleen
- stomach
Superior Mesenteric Artery (SMA) profuses?
- pancreas
- small intestine
- proximal colon
Inferior Mesenteric Artery (IMA) profuses?
-distal colon
Layers of the Gut wall
- Mucosa
- Submucosa
- Muscalaris externa
- Serosa
Layers of Mucosa
- Epithelium
- the lamina propria
- muscularis mucosae
Absorptive enterocytes
-play vital role in digestion and absorption
Enteroendocrine cells
- releases regulatory peptides & amines to regulate GI function
- sensor cell
Gastric Mucosal cells
produce protons
Where can you find the submucosal plexus (Meissner’s plexus)?
submucosa (located just underneath mucosal layer)
Where can you find the myenteric plexus?
In muscularis externa between the inner circular muscle layer and the outer longitudinal muscle layer
Function of Serosa
lubricate/protect organ
Histamine
- paracrine
- released by ECL in stomach, diffuses through the interstitial space and binds to neighboring parietal cells that secrete HCL
Serotonin
- Paracrine
- regulate contractile activity of smooth muscle cells in GI system
- released from enteric neurons, mucosal mast cells, special EECs
Cholecystokinin
- Paracrine and Endocrine
- acts locally on nerve terminals
- travels to pancreas
- released from duodenum
- CCK1
What innervates the upper one-third of the esophagus?
Cranial nerve VII & IX
Where do the pelvic nerves innervate?
The distal part of the colon and anorectal region