Metabolism Flashcards

1
Q

Describes all of the chemical reactions that take place in an organism.

A

Metabolism

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2
Q

What is the goal of metabolism?

A

Convert initial substrate

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3
Q

A series of interconnected biochemical reactions that convert a substrate through a series of metabolic intermediates, eventually resulting in a final product or products

A

Metabolic pathway

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4
Q

Two types of metabolism:

A

Anabolism and catabolism

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5
Q

The four general stages in the biochemical
energy production:

A

Stage 1: Digestion
Stage 2: Acetyl group formation
Stage 3: Citric acid cycle
Stage 4: Electron transport chain and oxidative phosphorylation

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6
Q

Where does digestion begin?

A

Mouth

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7
Q

What is the end product of digestion?

A
  • Glucose and monosaccharides
  • Amino acids
  • Fatty acids and glycerol
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8
Q

Where does acetyl group formation occurs?

A

Cytosol and mitochondria

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9
Q

The end product of acetyl group formation?

A

acetyl CoA and reduced coenzyme NADH

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10
Q

Where does citric acid cycle take place in?

A

Mitochondria

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11
Q

What is the end product of citric acid cycle?

A

CO2 and energy

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12
Q

In citric acid cycle, citrate is turned into?

A

Isocitrate

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13
Q

In citric acid cycle, Isocitrate is turned into?

A

a-ketoglutarate

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14
Q

In citric acid cycle, a-ketoglutarate is turned into?

A

Succinyl-Coenzyme A

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15
Q

In citric acid cycle, Succinyl-Coenzyme A is turned into?

A

Succinate

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16
Q

In citric acid cycle, Succinate is turned into?

A

Fumarate

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17
Q

In citric acid cycle, Fumarate is turned into?

A

Malate

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18
Q

In citric acid cycle, Malate is turned into?

A

Oxaloacetate

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19
Q

In citric acid cycle, Oxaloacetate is turned into?

A

Citrate

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20
Q

Where does electron transport chain occur?

A

mitochondria

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21
Q

The end product of electron transport chain

A

ATP

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22
Q

the molecule that makes energy available within all cells.

A

Adenosine triphosphate (ATP)

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23
Q

The energy currency of the cell

A

Adenosine triphosphate (ATP)

24
Q

True or false: Adenosine is a nucleoside

25
What is ATP comprised of?
nitrogen-containing base (adenine), a sugar (ribose), and three phosphate groups
26
Organelles most responsible for energy conversions. They can also multiply and increase their numbers when energy demands increase.
Mitochondria
27
Catalysts that do not get incorporated into the products of their reaction.
Enzymes
28
Requires oxygen to metabolize glucose and produce ATP
Aerobic cellular respiration
29
Aerobic cellular respiration has three stages:
- Glycolysis. - The citric acid cycle. - The electron transport chain
30
Glucose has how many carbons
Six
31
Where does glycolysis occur?
Cytoplasm
32
Which steps in glycolysis uses 1 ATP each?
Steps 1 and 3
33
Which steps in glycolysis produce 2 ATP?
Steps 7 and 10
34
The first set of reactions animals use to harvest energy occurs in the cytoplasm.
Glycolysis
35
10-step metabolic pathway by which glucose is converted to two molecules of pyruvate (a C₃ molecule)
Glycolysis
36
End product of glycolysis?
Pyruvate
37
The control ponts of glycolysis:
Steps 1, 3, and 10
38
Both pyruvate kinase (Step 10) and phosphofructokinase (Step 3) are?
allosteric enzymes
39
How many ATP are produced in krebs cycle
2
40
How many ATP are produced during glycolysis and the net gain.
4; 2
41
How many ATP are produced in skeletal muscle and nerve cells
30
42
How many ATP are produced in heart and liver cells
32
43
Is the series of biochemical reactions in which the acetyl portion of acetyl CoA is oxidized to carbon dioxide and the reduced coenzymes FADH₂ and NADH are produced
Citric Acid Cycle
44
Also know as: - Tricarboxylic acid cycle (TCA) - Presence of three carboxylate groups in citric acid - Krebs cycle - Named after Hans Krebs who elucidated this pathway
Citric Acid Cycle
45
Krebs cycle is named after:
Hans Krebs
46
Important reactions in the citric acid cycle include:
Reduction and decarboxylation
47
In every turn of CAC it produces:
2 CO2, 1 ATP, 3 NADH, 1 FADH2
48
Series of biochemical reactions in which intermediate carriers aid the transfer of electrons and hydrogen ions from NADH and FADH₂
The Electron Transport Chain
49
Complex I of ETC:
NADH–coenzyme Q reductase
50
Complex II of ETC:
Succinate–coenzyme Q reductase
51
Complex III of ETC:
Coenzyme Q–cytochrome c reductase
52
Complex IV of ETC:
Cytochrome c oxidase
53
Two mobile electron carriers
Coenzyme Q and cytochrome c
54
Process by which ATP is synthesized from ADP using the energy released in the electron transport chain
Oxidative phosphorylation
55
Pairs of biochemical reactions that occur concurrently in which energy released by one reaction is used in the other reaction
Coupled reactions
56
is used in a versatile set of metabolic pathways—the pathways can do much more than metabolize glucose
Anaerobic cellular respiration