Cell Anatomy & Physiology 3 Flashcards
A cell’s characteristic is determined by the type of proteins produced. True or false?
True
The proteins produced are in turn determined by the genetic information in the nucleus. True or false?
True
Information in protein provides the cell with a code for its cellular processes. True or false?
False, it should be DNA not proteins
DNA contains the information that directs protein synthesis; a process called ________
Gene expression
A DNA molecule consists of __________ joined together to form two ___________ strands
nucleotides
Each nucleotide consists of what?
5-carbon sugar, a phosphate group, and a nitrogenous base
a sequence of nucleotides that provides a chemical set of instructions for making a specific protein
Gene
- Found within the cell nucleus
- Stores and transfers genetic information
= Passed from existing cells to new cells during cell division
Deoxyribonucleic acid (DNA)
- Occurs in all parts of the cell
- Vital in the synthesis of proteins
Ribonucleic acid (RNA)
The main structural difference between ribose and 2-deoxyribose is the absence of oxygen on the 1st carbon (counterclockwise from O). True or false?
False, it’s the absence of oxygen on the 2nd carbon
Ribose is present in ____
2-deoxyribose is present in _____
RNA ; DNA
How many nitrogenous heterocyclic bases in nucleic acids?
5 nitrogenous heterocyclic bases
Give the 3 pyrimidine derivatives
- Cytosine (C)
- Thymine (T; found only in DNA),
- Uracil (U; found only in RNA)
Give the 2 purine derivatives
Adenine (A) and Guanine (G)
- Derived from phosphoric acid (H₃PO₄)
- Loses 2 hydrogen atoms, resulting in the formation of a hydrogen phosphate ion (HPO₄2–)
Phosphate
Amounts of A and G were always equal. Amounts of C and U were always equal. True or false?
False, A = T/U ; C = G
Human DNA contains:
30% adenine
30% thymine
20% guanine
20% cytosine
True or false?
True
Guanine always pairs with cytosine, adenine always pairs with thymine in DNA and uracil in RNA aka ___________
complementary pairs
explains the process in which the genetic information flows from DNA to RNA (i.e. gene expression) to make a functional protein product (protein synthesis)
central dogma of molecular biology
creates more copies of DNA using pre-existing DNA as templates
Replication
information from DNA is transferred to a single-stranded RNA
Transcription
RNA enters the ribosome which takes the information and synthesizes long polypeptide chains of amino acids
Translation
DNA replication is catalyzed by __________ which ensures correct base pairing and formation of phosphodiester linkages
DNA polymerase
The other strand grows in segments in the opposite direction
Okazaki fragments
The segments are connected by
DNA ligase
DNA replication usually occurs at multiple sites within the molecule. _____________ occurs at these sites while _____________ enables rapid replication of large molecule
Bidirectional replication ; Multiple-site replication
formed by the interaction of newly-replicated DNA molecules with histones
Chromosomes
A segment of a DNA strand responsible for the production of a specific hnRNA/mRNA molecule
Gene