Metabolism Flashcards

1
Q

What is metabolism?

A

Sum total of all chemical reactions that take place
with in the body

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2
Q

Metabolism is also referred to as what?

A

The use of foods to provide energy or make cellular products

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3
Q

Metabolism can be divided to what two major processes?

A

catabolism and anabolism

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4
Q

What is Catabolism?

A

the chemical reaction that breaks chemical bonds

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5
Q

How are chemical bonds broken?

A
  • Breaks molecules down into smaller molecules,
    releasing energy
  • Releases energy stored as chemical bonds
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6
Q

What are the two forms of energy?

A
  • work (40%)
  • heat (a waste product)
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7
Q

How does anabolism take place?

A
  • Energy is stored in the formation of chemical bonds
  • Builds nutrient molecules into larger compounds needed by the body
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8
Q

What happens to the energy released by catabolic reaction?

A

is used to fuel anabolic reactions

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9
Q

Energy usually takes the form of what?

A

ATP

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10
Q

How is energy transferred?

A

Oxidation-reduction reactions

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11
Q

What is oxidation?

A

loss of electrons
- Removal of hydrogens

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12
Q

What is reduction

A

gain of electrons
- Gain of hydrogens

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13
Q

How is ATP formed?

A

Phosphorylation
- ADP + P + energy →ATP

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14
Q

What elements are carbohydrates made of?

A

carbon, hydrogen, and oxygen ((CH20)x)

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15
Q

The fate of sugars depends on the needs of body: in what other ways can sugar be used?

A

ATP production, amino acid synthesis, nucleotide synthesis, lipid synthesis

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16
Q

How does aerobic respiration begin?

A

Glucose enters cells by facilitated diffusion

Once it enters, it is phosphorylated (stick phosphate to glucose to trap it in the cell so no come out again), thus preventing it from leaving cell

Overall reaction @ end (in the presence of O2

17
Q

What chemical reaction is responsible for the production of CO2?

A

C6H12O6 + 6O2 ➔ 6CO2 + 6H2O

18
Q

What type of reactions occurs during aerobic respiration?

A

Series of oxidation-reduction reactions

  • Glucose is oxidized to CO2
  • Oxygen is reduced to water
19
Q

What is aerobic respiration?

A

A chemical process in which oxygen is used to make energy from carbohydrates (sugars)

20
Q

What three majors steps are involved in aerobic respiration?

A
  • Glycolysis:
  • Kreb’s (Citric acid) cycle
  • Electron transport system
21
Q

Where does glycolysis occur?

A

in the cytoplasm

22
Q

Where do Kreb’s cycle and Electron transport system occur?

A

the mitochondrion

23
Q

Which step of aerobic respiration produces the most ATP?

A

Electron transport system

24
Q

What is the first step of cellular respiration?

A

glycolysis

25
Q

What is glycolysis?

A

A series of 10 reactions which break glucose down into two 3 carbon molecules

Occurs in cytoplasm

Does not require oxygen

26
Q

What types of respiration/s does glycolysis occur in?

A

Occurs in both aerobic and anaerobic respiration

27
Q

How does glycolysis occur?

A

Glucose, a 6 carbon sugar, is converted to two 3 carbon molecules, pyruvate (3-carbon)

  • Electrons are removed from glucose (oxidate)
  • NAD+ (grabs electron and gives it to someone else) is reduced to NADH (has electron)
  • Electrons are used to create ATP in later reactions
28
Q

What investment is required in glycolysis to start the process?

A

2 ATP molecules

29
Q

What are the final products of glycolysis?

A

2 ATP (net gain)
2 pyruvates
2 NADH

30
Q

If oxygen is present after glycolysis, what occurs?

A

move on to the Kreb’s cycle

31
Q

What happens after glycolysis during anaerobic respiration?

A

fermentation

32
Q

What processes happen before the Kreb’c cycle begins?

A

Pyruvate is transported into the mitochondrion’

Carbon removed as CO2

Electrons are removed and given to NAD+ to form to form NADH

Acetate binds with coenzyme A to form acetyl CoA (acetate= 2 carbon)

Process occurs twice for 1 glucose molecule (pyruvate)

33
Q

How does the Kreb’s cycle occur?

A

Acetyl CoA combines with oxaloacetate produces
- Citric acid
- CoA is released to find another pyruvate

Citric acid goes through a series of reactions
- 2 carbons are removed to form 2 molecules of CO2
- Final product is oxaloacetate, and the process begins again

34
Q

How are electrons removed during the Kreb’s cycle?

A

Electrons are removed in 4 steps
- 3 give electrons to NAD+ to form NADH
- 1 gives electrons to FAD to form FADH

35
Q

What is the product/result of Kreb’s cycle?

A
  • One ATP is produced
  • Process can occur twice for one molecule of glucose from glycolysis
  • Electron carriers can go on to form more ATP
36
Q

Where does the Electron Transport system occur specifically?

A

Occurs in mitochondrion in the Inner membrane

37
Q

How does the Electron Transport system occur?

A

Takes high energy electrons from carriers (e.g. NADH) and gives them to a series of electron carriers in the mitochondrial membrane

As the electrons are passed from carrier to carrier, energy is released and is used to form ATP
- Oxidative phosphorylation (requires O2 for the electron to produce H2O)

Oxygen is used as the final electron acceptor
- H2O (produces this)

38
Q

What is oxidative phosphorylation?

A

a cellular process that harnesses the reduction of oxygen to generate high-energy phosphate bonds in the form of adenosine triphosphate (ATP)

39
Q

What is the final product of the Electron Transport System?

A

For every NADH that gives electrons to ETS, 2.5 ATP are formed

For every FADH2 that gives electrons, 1.5 ATP are formed

The final yield of ATP from 1 molecule of glucose is 30-32 ATP, if oxygen was present