Metabolims Flashcards

1
Q

How much of diet is carbs?

A

48-50%

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2
Q

How much diet is protein?

A

15-16%

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3
Q

How much diet is fat?

A

32-33%

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4
Q

Makeup of carbs?

A

50-60% plant starches

30-40% disaccharides

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5
Q

Makeup of protein?

A

70-100 mg diet

35-200 g endogenous proteins utilized

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6
Q

Makeup of fat?

A

90% from triglycerides

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7
Q

Stomach digestion includes?

A

Pepsin, acid, lipases

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8
Q

How much lipid is digested from sublingual & gastric lipases?

A

15%

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9
Q

How efficient are we at using energy provided from food?

A

25%

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10
Q

How much of resting metabolic rate is used to maintain Na+/K+ pumps?

A

60%

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11
Q

What kind of calorimetry is Lavoisier

A

Direct

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12
Q

Atwater-Rosa Calorimetry

A

Manometer measures how much CO2 was taken out of filtered air & how much O2 must be put in (=O2 absorption rate)

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13
Q

Higher metabolic rate leads to what in one-way spirometry?

A

Faster decrease in O2 volume, quicker decline

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14
Q

Formula for glucose

A

C6H12O6

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15
Q

Amount of calories per liter O2 carbs

A

5.0 kcal/l O2

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16
Q

Amount of calories per liter O2 fat?

A

4.7 kcal/l O2

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17
Q

RER fat?

A

0.71 (55/78)

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18
Q

RER carbs?

A

1.0

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19
Q

formula for TAG

A

C55H104O6

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20
Q

% Calories from Carbs equation

A

RQ- 0.71/0.29

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21
Q

0.82 RER

A

Between meals (38%) calories from CHO

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22
Q

0.85 RER

A

Right after meal (48%) calories from CHO

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23
Q

0.90

A

High work intensity (65%)

from CHO

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24
Q

1.0

A

Highest anaerobic work intensity (100% ) from CHO

25
Q

Graph for exercise intensity & RER

A

RER v. Time

26
Q

What causes the maniac speed to go above 1?

A

Blowing off excess CO2

27
Q

Basal Metabolic Rate

A

Lowest rate of metabolism/caloric expenditure the body has under complete resting conditions

28
Q

What is BMR not?

A

Not minimal functional activity of the body- energy exchange is 10% lower during sleep

29
Q

What affects BMR?

A

Body size- in terms of kcal/weight not kcal/weight
Sex- Women has 6-10% lower BMR
Age
Food intake

30
Q

Specific Dynamic Action

A

Heat ingestion that causes BMR to increases above BMR

31
Q

What is the alactacid debt used for?

A

Rapidly replenish ATP, phosphagen, myoglobin & hemoglobin O2

32
Q

What is the lactacid debt used for?

A

Greater O2 uptakes is needed to get rid of metabolic intermediates that filled during the exercise (such as lactic acid)- used up or restored

33
Q

Which debt is the slow component?

A

Lactacid debt

34
Q

What can VO2 max be used to measure?

A

Aerobic fitness

higher for less fit, lower for more fit bc of more mitochondria

35
Q

What is the greatest stimulus for greater O2 intake?

A

ADP (turn on oxidative phosphorylation

36
Q

What would an increase in lactic acid intermediate do to RER?

A

Cause more of a need of bicarbonate, less CO2 blown off, RER goes down–>more aerobic exercise

37
Q

What does aerobic fitness/VO2 max come from?

A

50% efficiency increase in cardiovascular system

50% from increased number & size of mitochondria (more mito, can work not as hard)

38
Q

What is the effect of epinephrine in high exercise state?

A

Adrenergic effect of increasing muscle glycogen use & begin to use liver glycogen
Glycogen sparing effect

39
Q

Teleological reason why there would not be a glycogen sparing effect?

A

Wouldn’t want to run out of muscle glycogen when running away from fox

40
Q

What is the lactacid debt?

A

Increased O2 being used t create energy in order to get rid of intermediates

41
Q

What is the value when intensity of exercise is increased, but VO2 max doesnt increase?

A

VO2 max

42
Q

What 2 things cause increase in VO2 max?

A

-Efficiency of cardiovascular system (increase metabolic machinery)
-Increased number & size of mitochondria (metabolic machinery)
Training increases this- more aerobic

43
Q

Resting heart rate?

A

72 bpm

44
Q

About how long does it take to get to steady state after starting exercise?

A

1-2 minutes

45
Q

Resting ventilatory rate?

A

12 resp/minute

46
Q

Primary driving force for ventilatory rate?

A

pCO2–>H+ ions in brain

Except during exercise?

47
Q

What causes systolic pressure to go up during exercise?

A

Cardiac rate up–>venous return up bc of muscle contractions –>cardiac output up–>arterial blood pressure up

48
Q

What causes diastolic BP to go down during exercise?

A

Working skeletal muscles blood vessels vasodilate (skeletal muscle pump) drops diastolic BP

49
Q

What happens to mean arterial pressure during exercise?

A

Flatter line

50
Q

What is the rate limiting resource during low intensity, long time period exercise?

A

Blood glucose

51
Q

Primary rate limiting resource during moderate intensity, moderate time exercise(75% of max VO2)?

A

Depletion of muscle glycogen

52
Q

Primary rate limiting resource during high intensity, short exercise?

A

lactic acid buildup causes dissociation under body pH into free H+ ions & free hydrogen ions bind directly to myosin
Action potential crosses nerve/muscle membrane (sodium in, K+ out)

53
Q

What would cause diastolic blood pressure to go up?

A

Atherosclerosis(Arteriosclerosis)- can’t squeeze as much out of the artery

54
Q

What is the driving force of the blood flow?

A

Blood pressure

55
Q

What happens to a muscle as you change speeds over a long term exercise?

A

Glycogen phosphorylase gets turned off an on again, causes the glycogen to be used up faster

56
Q

What energy source is used for a low moderate exercise?

A

Liver glycogen- glycogen sparing effect of muscle glycogen

57
Q

What energy source is used during high intensity exercise?

A

Muscle glycogen because of high epinephrine levels to keep glycogen phosphorylase turned on by sympathetic stimulation

58
Q

What role does muscle glycogen play in exercise?

A

Protective effect-
Can’t breakdown muscle glycogen if exercise contractions are constant
No phosphatase like the liver so that glycogen could come out of the muscle

59
Q

Another reason why high intensity exercise causes fatigue?

A

Nerve action potential causes Na+ in & K+ out into extracellular fluid within the small T tubule –> causes depolarization, but repolarization can’t happen bc of K+ out can’t come back in & repolarize under high intensity exercise