Metabolic Pathways Flashcards

1
Q

The activity of AST requires which vitamin as coenzyme?

A

Vitamin B6

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2
Q

Vitamin B1 / Thiamine is used as a cofactor of what enzymes? (4)

A

Pyruvate dehydrogenase
Alpha-ketoglutarate dehydrogenase
Branched-chain Amino Acid Dehydrogenase
Transketolase

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3
Q

Vitamin B6 / Pyridoxine is used as a cofactor of what enzymes? (6)

A
  1. GOT/AST , GPT/ ALT
  2. Decarboxylation of glutamate & histidine
  3. ALA Synthase
  4. Cystarhionine synthase
  5. Synthesis of Niacin from Tryptophan (W)
  6. Glycogen phosphorylase
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4
Q

Heme Synthesis Substrates ?

A

Allan Puts His Untiring Care, Parents Proud of Heme.

Alasynthase
Porphobilinogen
Hydroxymethylbilane
Uroporphyrinogen
Coproporphyrinogen
Protophorhyrinogen
Protophorphyrin
Heme

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5
Q

Vitamin B12 / Cobalamin is used as a cofactor of what enzymes? (2)

A

Methionine Synthase
Methylmalonyl CoA mutase

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