Bioenergetics Flashcards
What is done through coupling reactions where a phosphate group is transferred to ADP from another substance with higher 🔼G?
Substrate Level Phosphorylation
This provides the greatest quantitative source of high energy phosphate in aerobic organisms.
Oxidative Phosphorylation
This process produces the chemical gradient that drive the generation of ATP from ADP according to chemiosmotic theory of how oxidation and phosphorylation are coupled.
Electron Transport Ejects H+ into the Intermembrane Space
Form of energy in electron transport chain that converts oxidation - reduction reactions into a form that can be used for the synthesis of ATP and for the uptake of solutes
Proton Gradient Only
Action of Cytochrome described in cases of acute cyanide poisoning wherein cyanide binds to Fe3+ of the cytochrome
Binds Carbon Monoxide
Metabolic effect of addition of an uncoupling agent to respiring mitochondria carrying out oxidative phosphorylation.
ATP formation ceases but O2 consumption continues
What is the other name for Complex I?
NADH: CoQ Oxidoreductase
Name the Inhibitors for Complex III.
Antimycin A and Dimercaprol
Name the inhibitors of Complex I
- Barbiturates
- Piericidin A
- Amytal
- Rotenone
( Barbie Pierce Amy and Rot)
Name the Inhibitors of Complex IV
“-ide”
1. Cyanide
2. Carbon monoxide
3. Sodium azide
4. Hydrogen Sulfide
Identify the compounds that increase the permeability of the inner mitochondrial membrane to protons
- Synthetic 2,4 dinitrophenol
- Aspirin
- Uncoupling protein: Thermogenin ( Brown Fat)
(DAT)
Complex V inhibitor
Oligomycin
This compound inhibits oxidative phosphorylation by inhibiting the transporter of ADP into ATP out of the mitochondrion
Atractyloside
What cycles happens in the Mitochondrial matrix? (3)
Krebs Cycle
Urea Cycle
B-oxidation
What cycle happens in the Inner Mitochondrial Membrane ? (3)
ETC
Succinate DH
ATP Synthase
