Cell Biology & Immunology

Question 1

What are acute inflammatory responses associated with prostaglandin release?

Answer 1

1. Vasodilation
2. Vasoconstriction
3. Increased Vascular permeability
4. Chemotaxis
5. Leukocyte adhesion

Question 2

Which complement system starts when antibody binds to bacteria?

Answer 2

Classical

Question 3

Which complement system starts spontaneously?

Answer 3

Alternative

Question 4

Which complement system starts with binding to mannose on bacteria?

Answer 4

Lectin

Question 5

Which complement system requires antigen-antibody complexes for activation ?

Answer 5

Classical

Question 6

Which complement system C3-convertase and activates component C3 complement?

Answer 6

1. Classical
2. Alternative
3. Lectin

Question 7

Does inflammation facilitate the spread of infection?

Answer 7

No

Question 8

Are acinar cells essential for the initiation of inflammation?

Answer 8

No

Question 9

Cells that initiate inflammation have surface or intercellular receptors called _______ receptors.

Answer 9

Pattern Recognition Receptors

Question 10

Found in the hepatic sinusoids , what cells initiate the process of inflammation?

Answer 10

Kupffer cells

Question 11

Is serotonin produced during inflammation?

Answer 11

No

Question 12

Activated platelets stimulate vasoconstriction through this compound.

Answer 12

Thomboxane A2

Question 13

Action of heparin which is a rapidly acting, potent anticoagulant.

Answer 13

Activates anti-thrombin III

Question 14

Factor deficient in a child with suspected congenital deficiency in coagulation presenting with normal PT, PTT, Fibrinogen , platelet aggregation, vW, then plasma was incubated with thrombin and Ca+2 with the clot dissolved in the presence of urea.

Answer 14

Factor XIII

Question 15

Activated PC (aPC) binding to the endothelia protein C receptor (EPCR) leads to the activation of this protein which elicits cytoprotective and anti-inflammatory properties.

Answer 15

Protease activated receptor-I (PAR-1)

Question 16

Loss of fibronectin in some types of malignant cells is associated with______?

Answer 16

Reduced integrin-mediated cell adhesion

Question 17

Deficiency in this factor of homeostasis generally do nit appear clinically prior to age 15 and would manifest with recurrent deep vrin thrombosis, pulmonary embolism, and cerebral vein thrombosis.

Answer 17

Antithrombin III

Question 18

Deficiency in this protein can result in emphysema because the action of elastase is unopposed.

Answer 18

Alpha-1-antitrypsin

Question 19

Whey is shown to contain large amounts of which interleukin?

Answer 19

IL-6