Menopause Flashcards

1
Q

what is the menopause

A

end of a women’s periods

need to have no periods for >1 year to be in the menopause

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2
Q

what is the average menopause age

A

51 years

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3
Q

what is a late menopause

A

> 54 years

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4
Q

what is an early menopause

A

<45 years

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5
Q

what effects on the body does oestrogen have

A
secondary sexual characteristics 
hair distribution, body shape and fat distribution 
effect on collagen 
bone growth 
proliferated endometrium
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6
Q

how do you diagnose menopause

A

vasomotor symptoms
pattern of periods
blood tests

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7
Q

why does a single raised FSH and LH level not confirm menopause

A

because it can be raised by lots of things

  • prior to ovulation
  • stopping contraceptive pill
  • breastfeeding or certain medications

or as its released in a pulsatile fashion it could have just been measured when it was naturally high

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8
Q

what are some physical symptoms of the menopause

A
hot flushes 
night whats 
palpitations 
insomnia 
joint aches 
headaches
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9
Q

characteristics of a hot flush in menopause

A

last 3-5 mins
average 2 years
10% last for 15 years

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10
Q

what psychological symptoms are there of the menopause

A
mood swings 
irritability 
anxiety 
difficulty concentrating 
forgetfulness
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11
Q

what are sexual symptoms of the menopause

A

vaginal dryness

libido

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12
Q

what are some later symptoms of menopause

A
frequency 
recurrent UTIs 
dysuria 
incontinence 
dry hair and skin 
atrophy of breast and genitals
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13
Q

what is perimenopausal dysfunctional uterine bleeding

A

irregular periods
inter-menstrual bleeding
post menopausal bleeding

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14
Q

what conservative management can be done for menopausal symptoms

A
diet 
weight loss 
exercise 
lifestyle 
caffeine 
CBT 
mindfulness
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15
Q

how do you treat menorrhagia (heavy period)

A

mefanamic acid (NSAID which decreases blood supply to the womb)
tranexamic acid (stops breaking down clots?)
progesterone
intra-uterine system
endometrial ablation (scar lining of the womb)
hysterectomy

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16
Q

what hormonal replacement therapy options are there

A

oestrogen alone

oestrogen and progesterone

topical or oral

17
Q

what are some contraindications for HRT

A
breast cancer
undiagnosed abnormal vaginal bleeding 
endometrial cancer
pregnancy 
active thrombo-embolic disorder 
recent myocardial infarction 
active liver disease with abnormal LFT 
porphyria cutanea trade
18
Q

what are the benefits of HRT

A

symptoms control
quality of life
reduced osteoporotic fracture
reduced bowel cancer
possible protective against Alzheimers and Parkinson
HRT<10 years after menopause has fewer risks and less cardiovascular events

19
Q

risks of HRT

A
Venous thrombosis-embolism  
Cardio vascular accident 
Breast cancer 
gallbladder disease 
HRT >20 years after menopause has greater risk of harm
20
Q

what are some non HRT options

A

clonidine
SSRIs
Regelle