Mendelian Inheritance III

Question 1

what is included in a ptype

Answer 1

physical appearance, internal anatomy, physiology, behavior

Question 2

norm of rxn

Answer 2

determines how a rang of env determines ptype given certain genotype
for each given gtype, each ptype will be diff
distribution of env = distribution of ptype
not possible to predict ptypes of diff gtypes in new env

Question 3

define pedigree

Answer 3

family tree describing interrelastionships btwn parents and children

Question 4

rare autosomal dom

Answer 4

every affected person has an affected person
half of offspring of affected parent are also affected
occurs in both sexes

Question 5

rare autosomal recessive

Answer 5

neither parents affected
1/4 of offspring of unaffected parents are affected
both sexes

Question 6

what are the dominantly inherited disorders

Answer 6

7/1000
Achondroplasia (hetero); lethal if homo
Huntingtons(homo & hetero)

Question 7

what are the recessive inherited disorders

Answer 7

4000 diseases
2.5/1000
carriers are ptypically normal
Albinism, CF, hemochromatosis, PKU, spinal muscular atrophy

Question 8

why are recessive diseases more common than dom

Answer 8

carriers of rec are ptypically normal

Question 9

why do inherited disorders show variable frequency in diff human pops

Answer 9

historical geographic isolation of human pops

Question 10

key concepts for mendels inheritance

Answer 10

used sci approach to identify 2 laws
laws of prob
many traits and diseases follow mendel inheritance
inheritance patterns more complex than mendel inherit
ptypes are products of gtypes and env

Question 11

what does the physical basis of mendelian inheritance lie in

Answer 11

behavior of chrom

Question 12

chromosomal theory of heredity

Answer 12

genes have specific loci on chrom and chrom undergo independent assortment and segregation

Question 13

signif of morgan hunt experiments

Answer 13

first solid evidence associating a specific gene w a specific chromosome

Question 14

traits that make fruit flies good lab stuff

Answer 14

short gen time

only 4 pairs of chrom

Question 15

describe morgans experiment

Answer 15

mated male flies w white eyes (mutant) with females w red eyes
F1 gen had all red eyes
F2 had 3:1 red to white, but only males had whites

Question 16

conclusions of morgan exp

Answer 16

gene for eye color on X chrom

supported chrom theory of inherit

Question 17

define sex-linked gene

Answer 17

a gene on either sex chrom

follow specfic patterns of inherit

Question 18

inheritance of sex linked genes

Answer 18

humans and other mammals have 2 varieties of sex chromosomes, X and Y

chicken(Z-W): female (ZW), male(ZZ)
insect(X-O): female (XX), male(X)
bees(haplo-diplo): females (diploid), males(haploid)

Question 19

sex linked disorders

Answer 19

hemophilia
RG color blindness
duchenne muscular dystrophy